Business Wire

Exscientia Launches AWS AI-powered Platform to Advance Drug Discovery

Share

Exscientia plc (Nasdaq: EXAI) today announced it will be expanding its work with Amazon Web Services (AWS) to use the cloud provider’s artificial intelligence (AI) and machine learning (ML) services to power its platform for end-to-end drug discovery and automation.

Exscientia’s platform uses generative AI models and the scalability and flexibility of AWS to securely, quickly and efficiently design drug candidates that aim to better target specific diseases and patients, with the goal of accelerating early drug development at a lower cost. The industry-standard pace of drug discovery is hampered by conventional high-throughput screening (HTS) approaches, which involves outsourcing large-scale chemical synthesis and biological testing to contract research organisations. Exscientia deploys generative AI in its DesignStudio to ‘learn’ rather than to ‘screen’ for discoveries in vast chemical space. The company’s UK based AutomationStudio then synthesises and tests drug candidates that were identified by its DesignStudio as having high potential, making extensive use of state-of-the-art robotics to drive efficiency in the molecular synthesis process. Data from the testing completed at the AutomationStudio is then fed back to its DesignStudio to further improve its generative AI algorithms. By impacting both the screening stage and the synthesis and testing stage of drug discovery, Exscientia aims to accelerate the pace of drug development, closing the loop between in silico design and wet-lab synthesis.

Exscientia’s platform, which is built using AWS technologies, supports its Design-Make-Test-Learn (DMTL) loops and spans generative AI, active learning, ML, physics-based systems and many other predictive methods. It also draws on large language models via Amazon Bedrock, a fully managed service that makes high-performing foundation models from leading AI startups and Amazon, available through a unified application programming interface (API). Exscientia expects that ‘closing the loop’ of virtual design and physical experimentation on AWS will benefit its internal discovery projects as well as its collaborative programmes, such as with Sanofi, and potential future partnerships.

“Extending our collaboration with AWS beyond our DesignStudio to include the robotic automation of synthesis and testing of our molecular designs was the logical next step for Exscientia,” said John Overington, Ph.D., Chief Technology Officer of Exscientia. “We were seeking a solution that had flexibility and scalability, combined with high performance and generative AI capabilities. We also wanted a collaborator that is creative and passionate about life sciences. AWS ticks all of these boxes.”

“Our mission is to transform the way the biopharma industry invents impactful medicines, by pairing the best available human science, ingenuity and AI/ML tech expertise with innovative experimental automation technologies to increase the quality and capacity of drug design, discovery and development,” said David Hallett, Ph.D., interim Chief Executive Officer and Chief Scientific Officer of Exscientia. “By encoding, automating and integrating the loop of design, synthesis and testing with our generative design workflows in our new AutomationStudio, we have taken the next step to increase the speed of learning, and to reduce the time and cost of exploring new therapeutic alternatives. We believe that working with AWS will accelerate the achievement of our goal to deliver higher-quality, precision designed future therapies to patients in need, faster.”

“The cloud is transforming the life sciences industry and helping to accelerate the pace of innovation. We’re excited that Exscientia is expanding its use of AWS’ generative AI and ML solutions to further speed up the discovery of new treatments for patients,” said Patrick Lamplé, Principal Healthcare & Life Sciences Tech Strategist – Worldwide, at Amazon Web Services. “The use of AI is also enabling Exscientia to automate their labs and processes, which will help to lower the costs associated with drug development.”

About Exscientia

Exscientia is a technology-driven drug design and development company, committed to creating more effective medicines for patients, faster. Exscientia combines precision design with integrated experimentation, aiming to invent and develop the best possible drugs in the most efficient manner. Operating at the interfaces of human ingenuity, artificial intelligence (AI), automation and physical engineering, we pioneered the use of AI in drug discovery as the first company to progress AI-designed small molecules into a clinical setting. We have developed an internal pipeline focused on oncology, while our partnered pipeline extends to many other therapeutic areas. By leading this new approach to drug creation, we believe we can change the underlying economics of drug discovery and rapidly advance the best scientific ideas into medicines for patients.

For more information visit us on www.exscientia.com or follow us on LinkedIn @ex-scientia and X @exscientiaAI.

Forward-Looking Statements

This press release contains “forward-looking statements” within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Words such as “anticipates,” “believes,” “expects,” “intends,” “may,” “plan,” “projects,” and “future” or similar expressions (as well as other words or expressions referencing future events or circumstances) are intended to identify forward-looking statements. All statements, other than statements of historical facts, included in this press release are forward-looking statements. These statements include, but are not limited to, statements regarding the advantages of the company’s technology platform and its drug discovery programmes; the company’s belief that using generative AI will accelerate drug development; the anticipated benefits of the company’s expanded collaboration with AWS including the ability to accelerate discovery projects; the benefits of the use of robotic automation in drug design; the potential for entry into and the expansion of current and future partnerships; the potential for experimental automation technologies to increase the quality and capacity of drug design, discovery and development including to design new and more efficient treatments for patients; the company’s belief that its capabilities will enable it to invent the best drugs in an efficient manner; the company’s belief that it can change the economics of drug design and advance ideas into medicines; and the company’s business strategies, goals and approach to drug design. Any forward-looking statements are based on management’s current expectations and beliefs of future events and are subject to a number of risks and uncertainties that could cause actual events or results to differ materially and adversely from those set forth in or implied by such forward-looking statements, many of which are beyond the company’s control. These risks and uncertainties include, but are not limited to, the risk that the company’s platform technology may fail to discover and design molecules with therapeutic potential or may not result in the discovery and development of commercially viable products for the company or its collaborators; the company may be unable to advance its drug candidates through clinical development, regulatory approval or commercialisation; the impacts of macroeconomic conditions, including the conflict in Ukraine and the conflict in the Middle East, heightened inflation and uncertain credit and financial markets, on the Company’s business, clinical trials and financial position; the company’s ability to realise the benefits of its collaborations; changes in expected or existing competition; changes in the regulatory environment; the uncertainties and timing of the regulatory approval process; and unexpected litigation or other disputes. These and other risks and uncertainties are described in the “Risk Factors” section of Exscientia’s Annual Report on Form 20-F for the year ended December 31, 2023, filed with the Securities and Exchange Commission (SEC) on March 21, 2024, and well as discussions of potential risks, uncertainties and other factors in Exscientia’s subsequent filings with the SEC. All information in this press release is as of the date of the release, and the Company undertakes no duty to update this information, except as required by law.

View source version on businesswire.com: https://www.businesswire.com/news/home/20240710764372/en/

Contacts

Investor Relations:
Sara Sherman / Chinedu Okeke
investors@exscientia.ai

Media:
David Keown
media@exscientia.ai

(c) 2024 Business Wire, Inc., All rights reserved.

Business Wire, a Berkshire Hathaway company, is the global leader in multiplatform press release distribution.

Subscribe to releases from Business Wire

Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.

Latest releases from Business Wire

Suzano Agrees US$110 Million Purchase of Two US Industrial Facilities from Pactiv Evergreen13.7.2024 00:29:00 CEST | Press release

Suzano, the world's largest pulp producer, has announced the acquisition of industrial assets from Pactiv Evergreen in the United States. This will expand the company’s operations in North America and marks its entrance into the consumer and food service packaging segments in the region. The transaction is valued at US$110 million and includes two mills in Pine Bluff, Arkansas, and Waynesville, North Carolina, that manufacture liquid packaging board and cupstock. Subject to final regulatory approval expected later this year, these assets will add approximately 420,000 metric tonnes annually of integrated paperboard to Suzano’s production capacity. Alongside the acquisition, Suzano has signed a long-term supply deal with Pactiv Evergreen to provide liquid packaging board for its converting business. Suzano is currently the largest supplier of hardwood market pulp in North America, with US offices in Fort Lauderdale, Florida, and a research and innovation campus close to Vancouver, Canad

Oakio Set to Participate in Batimat Paris 2024 with Innovative WPC Solutions12.7.2024 15:47:00 CEST | Press release

Oakio, a pioneer in eco-friendly and high-performance wood-plastic composite (WPC) products, will be participating in the Batimat Paris 2024 exhibition. The event will be held from September 30 to October 3 at Paris Expo Porte de Versailles, offering a premier platform for showcasing the latest advancements in the construction and building materials industry. Batimat is a globally recognized event that brings together industry leaders, innovators, and professionals to explore the newest trends and technologies in construction. Oakio will be exhibiting at Booth H1-A066, where attendees can discover the full range of Oakio’s innovative products. "We are delighted to be part of Batimat 2024 and to present our comprehensive range of sustainable building solutions," said Juno Zhong, Marketing Director at Oakio. "Our products are designed to meet the growing demand for environmentally responsible and high-performance materials in both residential and commercial projects." The products showca

Nord Anglia Education and Boston College to Demonstrate the Power of Metacognition at the European Conference on Education12.7.2024 15:16:00 CEST | Press release

Dr Kate Erricker, Group Head of Education Research and Global Partnerships at Nord Anglia Education, and Dr Damian Bebell, Assistant Professor at the Lynch School of Education and Human Development, Boston College, will lead a workshop on metacognition at the European Conference on Education (ECE) on Saturday 13 July 2024. Titled “Exploring the Implementation and Outcomes of a Global Metacognition Project”, the workshop will explore how metacognition can improve learning in classrooms and showcase Nord Anglia Education’s pioneering metacognition research project involving 27 schools in 17 countries. Metacognition is being aware of and controlling one’s own learning processes. Studies have shown that metacognition can greatly enhance student learning. “Metacognition bridges the gap between knowledge and understanding,” says Dr Kate Erricker. “By teaching students to be aware of how they think and learn, we’re not just enhancing their academic performance but also preparing them for futu

BLS International Holding Anonim Şirketi (Turkey) Successfully Completes Acquisition of 100% Stake in iDATA12.7.2024 14:32:00 CEST | Press release

BLS International Services Limited, a leading global tech-enabled service partner for governments and citizens, announced the successful completion of the acquisition of 100% stake in iDATA and its wholly owned subsidiaries, through BLS International FZE (WoS of BLS) and BLS International Holding Anonim Şirketi (WoS of BLS International FZE). Turkey-based iDATA, a leading visa service provider with 37+ VACs in 15+ countries, serves Germany, Italy, and the Czech Republic. BLS acquired iDATA for ~Euro 80 Million. In 2023, iDATA reported revenues of ~Euro 27.3 Million and EBITDA of ~Euro 16 Million. This acquisition would further strengthen the overall BLS’ position as one of the leading international player in Visa and Consular services. iDATA’s existing agreements and offices will be aligned into the BLS’s network in 66 countries across the globe, enabling BLS to service more Client Governments in Europe. The transaction will be EPS (Earning per share) accretive to BLS immediately. Mr.

KKR and Palm Capital to Acquire Prime Last-Mile Logistics Asset in Denmark12.7.2024 14:30:00 CEST | Press release

KKR, a leading global investment firm, and Palm Capital, the pan-European real estate private equity specialist today announced the acquisition of a prime last-mile logistics asset in Greater Copenhagen, Denmark, from Catena, the Sweden-based leading logistics developer. The park comprises 47,000 sqm of warehouse and office space and hosts long-term tenant Nemlig.com, the country’s largest provider of direct-to-consumer online food and grocery delivery. The logistics asset is located in Greater Copenhagen and surrounded by excellent infrastructure, uniquely positioned on the city’s new light rail system, which is due to be completed in 2025. In a supply-constrained industrial real estate market with strong growth potential, the asset offers significant upside with potential for further development, including additional warehouse facilities and various asset management initiatives such as energy and asset improvements together with the tenant. Alexander Thams, Director and Head of Nordi

In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.

Visit our pressroom
HiddenA line styled icon from Orion Icon Library.Eye