NASDAQ OMX

Corline Biomedical AB: Etikprövningsnämnden ger godkännande till klinisk studie för Cytoparin

Dela

Corline Biomedical AB ("Corline") meddelar att den Regionala Etikprövningsnämnden i Uppsala på sitt möte den 4 maj 2016 beslutat godkänna begäran om ändring som inlämnats i den sedan tidigare godkända Cytoparin -studien, där Corline är sponsor och Tomas Lorant vid Akademiska sjukhuset är prövningsledare. Beslutet har publicerats på Etikprövningsnämndens hemsidan (www.epn.se).

Corline har sedan tidigare Läkemedelsverkets och Etikprövningsnämndens godkännande att starta en klinisk prövning med Cytoparin(TM) som medicinteknisk produkt. För att ansluta projektet till det nu gällande regelverket om cellbaserade produkter (avancerande terapiläkemedel, ATMP) och därigenom effektivisera utvecklingsprocessen, beslutade Corline 2015 om att lämna in en ny ansökan för att pröva Cytoparin(TM) som läkemedel. Etikprövningsnämnden i Uppsala har nu godkänt de begärda ändringarna för den kliniska studiens upplägg. Innan Corline kan starta studien återstår att erhålla Läkemedelsverkets godkännande. 

Cytoparin(TM)-studien görs i samarbete med Akademiska sjukhuset, Rikshospitalet i Oslo och Karolinska sjukhuset i Huddinge och syftar till att pröva om det är säkert och effektivt att använda Cytoparin(TM) för att skydda insulinproducerande celler vid transplantation till svårt sjuka patienter med diabetes typ 1. Idag upphör funktionen i upp till 70 % av de transplanterade cellerna inom den första timmen efter transplantation, eftersom cellerna angrips av mottagarens immunförsvar. Det gör att sjukvården i genomsnitt måste använda 2,7 donatorer för att behandla 1 patient. En transplantation kostar ungefär 800 000 kronor att genomföra och det råder en mycket stor brist på organ för transplantation. Genom att klä in cellerna med Cytoparin(TM) inför transplantationen är målet att cellerna skyddas och bibehåller sin funktion samt att användandet av organ därmed effektiviseras . Härigenom kan betydligt fler svårt sjuka patienter med diabetes typ 1 erbjudas behandling.

Henrik Nittmar, VD i Corline Biomedical AB, kommenterar
"Etikprövningsnämndens godkännande innebär ett viktigt steg på vägen mot studiestart i Cytoparin(TM)-projektet. Nu inväntar vi svar från Läkemedelsverket på vår ansökan om prövning som läkemedel."

Certified Adviser
Sedermera Fondkommission är Corlines Certified Adviser.

För mer information om Corline, vänligen kontakta
Henrik Nittmar, VD
Telefon: 018-71 30 90
E-post: henrik.nittmar@corline.se

Corline Biomedical AB arbetar med den kroppsegna substansen heparin och har utvecklat en portfölj med läkemedelskandidater för användning i anslutning till organ- och celltransplantation. Bolaget planerar kliniska studier inom diabetes typ 1 och njurtransplantation, för vilket Corline även har erhållit särläkemedelsstatus ("Orphan Drug"). Inom ramen för helägda dotterbolaget Corline Pharma AB utvärderas in vivo-administration av Corlines heparinsubstans och sedan tidigare ytbelägger bolaget medicintekniska produkter och har bland annat behandlat över 100 000 hjärtstentar som implanterats i patienter. De nya läkemedelskandidaterna är baserade på samma grundteknologi som de medicintekniska produkterna.




This announcement is distributed by NASDAQ OMX Corporate Solutions on behalf of NASDAQ OMX Corporate Solutions clients.
The issuer of this announcement warrants that they are solely responsible for the content, accuracy and originality of the information contained therein.
Source: Corline Biomedical AB via Globenewswire

HUG#2012162

Om

NASDAQ OMX
NASDAQ OMX



Följ NASDAQ OMX

Abonnera på våra pressmeddelanden.

Senaste pressmeddelandena från NASDAQ OMX

Algeco Scotsman Announces Debt Package for Refinancing, Acquisition of Touax Solutions Modulaires SAS and Exercise of Put Option10.12.2017 23:14Pressmeddelande

BALTIMORE, Md., Dec. 10, 2017 (GLOBE NEWSWIRE) -- Algeco/Scotsman Holding S.à r.l. (together with its subsidiaries, the "Algeco Group") today announced that a finance special purpose vehicle that will be a subsidiary of the Algeco Group has entered into a senior debt package arranged by a syndicate of lending institutions and a preferred stock facility with a group of other financing providers. The proceeds of this financing, or any debt issued in lieu of the loans under the facilities (which replacement debt could be in the form of loans, securities or other debt instruments, may be publicly or privately placed and may be denominated in euros or US dollars), will be used to refinance the existing capital structure of the Algeco Group, including its existing Senior Secured Notes due 2018 and existing Senior Unsecured Notes due 2019. In connection with this refinancing, a lending syndicate will provide a new $400 million senior secured asset backed facility. The debt package is continge

Elemica Wins Green Supply Chain Award8.12.2017 19:54Pressmeddelande

WAYNE, Pa., Dec. 08, 2017 (GLOBE NEWSWIRE) -- Elemica, the leading Business Network for the process industries, announces winning the Supply & Demand Chain Executive Green Supply Chain Award for 2017. This is Elemica's 9th consecutive win of this prestigious award that recognizes small, mid-size and large enterprises that leveraged green practices and solutions to further drive sustainable improvements in their supply chain. Elemica was chosen for helping clients improve and achieve measurable sustainability goals through the automation of manual processes, eliminating the use of paper and optimizing transportation processes through carrier collaboration and automated processes that reduce mileage. "This is a great honor for Elemica - recognition for nine consecutive years for helping clients meet their green and sustainability goals," said John Blyzinskyj, CEO of Elemica. "By utilizing Elemica's integrated cloud-based logistics and transportation products, customers have lowere

Constellation Brands to Report Third Quarter Fiscal 2018 Financial Results; Host Conference Call January 5, 20187.12.2017 22:37Pressmeddelande

VICTOR, N.Y., Dec. 07, 2017 (GLOBE NEWSWIRE) -- Constellation Brands, Inc. (NYSE:STZ) (NYSE:STZ.B), a leading beverage alcohol company, announced today it will report financial results for its fiscal third quarter ended November 30, 2017, on Friday, January 5, 2018, before the open of the U.S. markets. A conference call to discuss the financial results and outlook will be hosted by President and Chief Executive Officer Rob Sands and Executive Vice President and Chief Financial Officer David Klein at 10:30 a.m. eastern time, January 5, 2018.  The conference call can be accessed by dialing +973-935-8505 beginning at 10:20 a.m. (eastern). A live, listen-only webcast of the conference call will be available on the company's website, www.cbrands.com, under the Investors section. Financial information discussed on the conference call, and a reconciliation of reported (GAAP) financial measures with comparable or non-GAAP financial measures, will also be available on the company's websi

CTI Clinical Trial and Consulting Services Announces Acquisition of Eurotrials7.12.2017 21:00Pressmeddelande

COVINGTON, Ky., Dec. 07, 2017 (GLOBE NEWSWIRE) -- CTI Clinical Trial and Consulting Services (CTI), a global, privately held, full-service contract research organization announces the acquisition of Eurotrials, a full-service contract research organization, with more than 20 years of experience, and strong local expertise in Europe and Latin America. The acquisition strengthens CTI's existing Real World Evidence business, adding significant presence and expertise in Europe and Latin America. Eurotrials has offices in Argentina, Brazil, Chile, Mexico, Peru, Portugal and Spain, covering over 15 countries in both regions. Eurotrials provides an extensive array of services from early- to late-stage research as well as product support in accordance with global and specific regional requirements.  Additionally, the Eurotrials footprint augments CTI's current reach, enabling CTI to better serve clients and global programs. "We are excited to join our companies together t

DigitalTown Announces Global Launch of CityShares7.12.2017 19:29Pressmeddelande

Local Ownership Model for City Platform Cooperatives built on Blockchain SEATTLE, Dec. 07, 2017 (GLOBE NEWSWIRE) -- DigitalTown, Inc. (OTC PINK:DGTW), the leading provider of People-centric Solutions for Smart Cities, announced today the beginning of the free claim period for CityShares, or fractional interests, in its Smart City platforms across nearly 4 million cities, towns and villages around the world. The announcement makes it possible for any city to become a Smart City based on the DigitalTown platform. A PowerPoint presentation accompanying this announcement is available at  http://www.globenewswire.com/NewsRoom/AttachmentNg/6287d2a9-d481-4e0e-a162-9c3f224daeb1 Since the introduction of DigitalTown in London in June 2017, management at DigitalTown has been in discussions with stakeholders in cities and towns around the world to introduce its flagship Platform Cooperative for Cities. The groundbrea

Crown Bioscience Releases Scientific Posters Detailing Innovations in Preclinical Cancer Pharmacology7.12.2017 16:45Pressmeddelande

Presentation of Posters by Expert Scientists Now Available On-Demand on Crown Bioscience's Website  https://www.crownbio.com/eortc17-posters SANTA CLARA, Calif., Dec. 07, 2017 (GLOBE NEWSWIRE) --  Crown Bioscience, a wholly-owned subsidiary of Crown Bioscience International (TWSE:ticker 6554) and a global drug discovery and development services company providing translational platforms to advance oncology, inflammation, cardiovascular and metabolic disease research, releases scientific posters narrated by leading scientists. These posters were presented at the recent AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics and are now available on-demand on Crown Bioscience's website,  https://www.crownbio.com/eortc17-posters. Crown Bioscience presented more than a dozen scientific posters describing innovations in the field of preclinical cancer research at AACR-NCI-EORTC 2017. The most compelling work is now available

I vårt pressrum kan du läsa de senaste pressmeddelandena, få tillgång till pressmaterial och hitta kontaktinformation.

Besök vårt pressrum