Grünenthal Group

Grünenthal is Recognized for its Strong Management of Environmental, Social and Governance (ESG) Risks

Dela
  • Leading global ESG ratings agency Sustainalytics notes Grünenthal is in the top five percent among its peers in the pharmaceutical subindustry
  • Grünenthal is categorized as “medium risk”, placing it ahead of its key subindustry peers and in the same league as multinational companies like Pfizer and Roche

 

Aachen, Germany, 7 April 2021 – Grünenthal, a global science-based pharmaceutical company, today announced that Sustainalytics, a Morningstar company and a globally-recognized provider of ESG research, ratings and data, has assessed it as having overall medium ESG risk. In addition, Sustainalytics acknowledged that Grünenthal has a strong management of its ESG risks. This places Grünenthal in the top five percent of the global pharmaceuticals subsector.

“The long-term success of companies can no longer be measured by financial success alone. As a science-based company, Grünenthal strives to make a net-positive impact on the society,” said Gabriel Baertschi, CEO Grünenthal. “While we are proud to see our efforts recognized in this ESG rating, we know that a big part of the journey is still ahead of us. Building on our foundation as a responsible business, we will now integrate sustainability even more closely in our core strategy.”

Grünenthal was evaluated by Sustainalytics based on its ESG Risk Ratings framework, which focuses on exposure and management of a company’s material ESG issues. “Exposure” reflects the degree to which a company’s enterprise value is exposed to material ESG issues including ethical marketing, clinical trial transparency, whistleblowing, corruption and bribery. “Management” measures a company’s preparedness and track record in managing its exposure to material ESG issues through its policies, programmes, trainings and management systems.

The company’s ESG Risk Rating is available on Sustainalytics’ website.All data mentioned is as of 6 April 2021 and refer to the Grünenthal Pharma GmbH & Co. KG.

About Grünenthal’s ESG efforts

Grünenthal has been focusing its Environmental, Social & Governance (ESG) efforts on four pillars: educate about pain treatment and responsible use of opioids; ensure access to medicines, innovate pain management, and raise awareness for “pain as a disease”:

Educate about pain treatment and responsible use of opioids
Grünenthal has so far reached around 65,000 health care professionals in its efforts to educate the healthcare sector about pain management and improve the patient outcomes from pain treatment. As a leader in pain innovation and as an opioid manufacturer, Grünenthal is highly committed to ensuring that its employees, customers, patients and also its partners have a thorough understanding of the company’s stance on the responsible medical use of opioids in pain. The company has fostered a mindset shift along the full value chain by ensuring that all opioid-related materials contain Grünenthal’s statement on responsible use of opioids – clearly highlighting the risks and benefits of this class of medicines. In addition, Grünenthal had established a dedicated standing governance body to provide and promote clear guidance, coherent behavior, continuous improvement, training and control mechanisms.

Ensure access to medicine
Grünenthal is committed to ensuring the availability of key medicines to address unmet medical needs in the markets we serve. In the US, for instance, 5 million patients are in need of neuropathic pain treatment associated with diabetes. With the US FDA label extension of one of our non-opioid pain medicines for the treatment of neuropathic pain associated with diabetic peripheral neuropathy of the feet, Grünenthal has ensured patients get access to this much needed treatment. At the same time, the company is focused on addressing unmet therapeutic needs in underserved markets by offering specialized non-opioid pain medicines.

Innovate pain management
Grünenthal’s research and development strategy focuses on tackling in pain and collaborating with partners to address the huge unmet needs in pain. Through biennial grants of €200,000 provided by Grünenthal and the EFIC, the company supports young scientists early in their career in carrying out innovative clinical pain research. Since foundation of the EFIC-Grünenthal Grant in 2004, approximately €1.6 million was awarded to fund 65 projects. In addition, to drive patient-centric innovation in chronic pain and neurological disorders and award patient-centric and scientifically robust innovation, the company supports the Brain, Mind, and Pain Patient-Centered Innovation Grant, which awards €90,000 biennially to research proposals to encourage patient-centered innovation that leads to improvements in the life conditions of pain patients.

Raise awareness for “pain as a disease”
Chronic pain is an enormous global health problem affecting around 10% of the world’s population. Grünenthal raises awareness about the impact of pain by supporting a multi-stakeholder platform, called the Societal Impact of Pain platform, which fosters the development of pain policies on national level. With Grünenthal’s Pain Toolkit, the company has established a practical tool that provides patients with handy tips and skills in the form of explanations, infographics and videos, on how to self-manage pain. Moreover, Grünenthal has a long-standing passion for preserving the dignity and quality of life at the end stage of people’s lives. The Grünenthal Foundation for Palliative Care promotes science and research in palliative care and the care for seriously or terminally ill people in Europe as well as in Latin America.

Besides these four focus pillars, Grünenthal is covering the entire range of the Environmental, Social and Governance spectrum with various initiatives and measures:

Environmental
Our efforts to promote sustainable development include defining concrete goals for the operations of our five production sites, across our supply chain and all of our affiliates across the globe by following leading international standards for environment, health and safety. We collect and analyze data from our production sites and use it to continuously improve efficiency, while also reducing energy consumption and minimizing waste based on strategic approach of zero waste to landfill programme.

Social
Caring for its employees and for the communities where we operate is key to Grünenthal’s business conduct. Grünenthal offer its employees an exciting working environment and wide-ranging individual development opportunities. It is the company’s goal to maintain high levels of engagement and to strengthen the company as a Great Place to Work®. Grünenthal promotes a vibrant, high-performance culture and brings it to live through a shared set of values. These are supported by specific behaviours that guide the decision-making. Grünenthal ensures outstanding results are recognised and rewarded. For example, the company celebrates exceptional contributions each year with its Grünenthal Global Excellence Award.

Governance
Sound governance is key to safeguard the company’s license to operate and continue providing medicines to patients in need. Grünenthal has a comprehensive compliance and ethics management system which provides a clear framework for our decisions and actions. Grünenthal’s Code of Conduct for employees reiterates the company’s strong commitment to the highest ethical standards while the Code of Conduct for Business Partners ensures business relationships based on a reciprocal commitment to responsible behavior. Grünenthal has an external Ethics Helpline for 24/7 anonymous reporting in place to ensure compliance with the Code of Conduct. Grünenthal is also committed to full disclosure of transfers of value to healthcare professionals, healthcare organizations and patient organizations.

Kontakter

Länkar

Om

Grünenthal Group
Grünenthal Group

Aachen, Germany

http://www.grunenthal.com

About Grünenthal

Grünenthal is a global leader in pain management and related diseases. As a science-based, privately-owned pharmaceutical company, we have a long track record of bringing innovative treatments and state-of-the-art technologies to patients worldwide. Our purpose is to change lives for the better – and innovation is our passion. We are focussing all of our activities and efforts on working towards our vision of a world free of pain.

Grünenthal is headquartered in Aachen, Germany, and has affiliates in 29 countries across Europe, Latin America and the US. Our products are available in more than 100 countries. In 2020, Grünenthal employed around 4,500 people and achieved sales of € 1.3 bn.

More information: www.grunenthal.com

 

Grünenthal GmbH, 52099 Aachen, Germany

Följ Grünenthal Group

Abonnera på våra pressmeddelanden. Endast mejladress behövs och den används bara här. Du kan avanmäla dig när som helst.

Senaste pressmeddelandena från Grünenthal Group

First participants enrolled in Clinical Trial with Nociceptin/Orphanin peptide receptor (NOP) agonist ​29.9.2021 10:55:16 CEST | Press release

Aachen, Germany, 29 September 2021 –Today, Grünenthal announced that the first participants have been enrolled in a randomised, placebo- and active-controlled clinical trial for its peripherally restricted Nociceptin/Orphanin FQ peptide receptor (NOP) agonist. The compound is being developed to provide a non-opioid therapy option that offers a strong analgesic effect without the side effects commonly associated with opioids. The Experimental Medicine Trial will evaluate the extent and duration of the pharmacological effect of the oral NOP agonist in an experimental pain model. The results of the trial are expected to be available in early 2022. The trial explores how the NOP agonist influences pain signalling and perception using laser evoked potentials (LEPs) in an experimental pain model with 30 healthy participants. On five different occasions, the participants will receive either the NOP agonist or pregabalin or placebo. The trial explores three different doses of the NOP agonist;

First patient enrolled into a Phase III study with QUTENZA® in post-surgical neuropathic pain ​10.8.2021 09:00:00 CEST | Press release

The study AV001 aims to include the treatment of post-surgical neuropathic pain (PSNP) in the U.S. label. QUTENZA® is currently approved for use in adults in the treatment of neuropathic pain associated with postherpetic neuralgia and for the treatment of neuropathic pain associated with diabetic peripheral neuropathy (DPN) of the feet. Post-surgical neuropathic pain is a debilitating complication of surgery that affects approximately 13% of all patients who undergo surgery, representing 3.3 million patients per year in the US.[1] Aachen, Germany, & Morristown, N.J., 10 August 2021 –Grünenthal announced today that its U.S. subsidiary, Averitas Pharma Inc., enrolled the first patient in the randomised, double-blind trial AV001. The Phase III study investigates the efficacy, safety, and tolerability of QUTENZA (capsaicin) 8% topical system in post-surgical neuropathic pain (PSNP) to support an extension of the U.S. label. The trial will include over 400 patients who suffer from moderate

Grünenthal’s Glucocorticoid Receptor Modulator enters clinical development27.7.2021 10:50:36 CEST | Press release

Aachen, Germany, 27 July 2021 –Grünenthal announced today that the first volunteers have been enrolled in a Phase I trial of its Glucocorticoid Receptor Modulator (GRM). The oral investigational medicine aims to provide a therapy option with broad anti-inflammatory efficacy and a more favourable benefit-risk profile compared to current glucocorticoid-based therapies like prednisolone. The Phase I trial includes 80 healthy volunteers and is designed as a head to head comparison between the GRM and prednisolone, the most frequently used glucocorticoid.[1] Observing several biomarkers, the trial will assess the influence of the investigational medicine on bone metabolism and glucose levels. Reduced bone formation leading to osteoporosis as well as increased blood glucose levels leading to an increased risk of diabetes are among the most common side-effects of glucocorticoids, which are a strong limitation for their long-term use at highly effective doses.[2],[3],[4] The results of the stu

Grünenthal acquires Mestex AG and its Phase-III-ready investigational medicine MTX-071 for the treatment of pain associated with osteoarthritis of the knee12.4.2021 11:25:16 CEST | Press release

With the acquisition of Mestex AG, Grünenthal secures global rights for an attractive late-stage asset that could offer an innovative therapy option for millions of patients affected by pain related to osteoarthritis of the knee. MTX-071 (resiniferatoxin) is a highly potent Transient Receptor Potential Vanilloid 1 (TRPV1) agonist. Its administration can reversibly defunctionalise TRPV1-expressing nociceptors. This can result in long lasting pain relief. Aachen, Germany, 12 April 2021 –Today, Grünenthal has announced the acquisition of Mestex AG through the takeover of all of its shares and options. Mestex AG is a Swiss biotech company that has developed the innovative investigational medicine MTX-071 (resiniferatoxin) for the intra-articular treatment of pain associated with osteoarthritis of the knee. The investigational medicine is currently concluding Phase II of clinical development and is about to enter Phase III. Initial data showed a long-lasting and significant analgesic effect

Grünenthal and Averitas Pharma announce initiation of Phase III study with QUTENZA® to prepare label extension in the US for the treatment of post-surgical neuropathic pain​30.3.2021 14:45:28 CEST | Pressmeddelande

Post-surgical neuropathic pain (PSNP) is a debilitating complication of surgery that affects approximately 13 percent of all patients who undergo surgery, which represents 3.3 million patients per year in the US.[1] This Phase III study is Grünenthal’s next step in making QUTENZA available to even more patients in the United States. QUTENZA is the first and only prescription strength capsaicin that is a topical, non-systemic, non-opioid pain treatment; it is currently approved in the US for the treatment of neuropathic pain associated with postherpetic neuralgia, and for the treatment of neuropathic pain associated with diabetic peripheral neuropathy (DPN) of the feet in adults. Aachen, Germany, & Morristown, N.J., 30 March 2021 –Grünenthal announced today that its U.S. subsidiary, Averitas Pharma, Inc. will conduct a Phase III trial to study the efficacy, safety and tolerability of QUTENZA (capsaicin) 8% topical system in post-surgical neuropathic pain (PSNP) with the goal to expand t

Grünenthal successfully extends its term loan bank facilities12.2.2021 13:51:16 CET | Pressmeddelande

Grünenthal has announced the successful extension of its existing €535 million term loan bank facilities. This amendment was conducted in the broader context of the company’s acquisition of the European rights (excluding Spain and the UK) to the lipid-lowering medication CRESTOR™ completed in February 2021. The term loan maturities are now aligned with Grünenthal’s Revolving Credit Facility maturity, which further extends its debt maturity profile. More than 60 percent of Grünenthal’s debt facilities now mature in 2024 or later. “By extending the maturity of our financing, we have gained additional flexibility to further fund our growth strategy,” says Fabian Raschke, Chief Financial Officer of Grünenthal. „We will continue to explore opportunities to further support our organic growth with targeted acquisitions, that fit our EBITDA and cash flows accretive acquisition strategy.“ Grünenthal’s capital structure has enabled it to enter into a series of acquisitions and partnerships in re

I vårt pressrum kan du läsa de senaste pressmeddelandena, få tillgång till pressmaterial och hitta kontaktinformation.

Besök vårt pressrum