Business Wire

KD Pharma Group & SLA Pharma Initiate Clinical Trial For COVID-19

Share

The KD Pharma Group (“KD Pharma”) and its partner, SLA Pharma (“SLA”), announced that its new drug candidate EPAspire™ is shortly entering clinical trials as a promising candidate to treat patients with symptoms of the novel coronavirus infection. The MHRA in the UK has approved the trial and late-stage discussions are ongoing with authorities in other European countries. Additionally, an application has been submitted to the FDA in the US. It is expected that the first patients in the trial will be enrolled shortly and additional hospital sites are being recruited for the trial.

“We hope EPAspire™ will be able to reduce the risk of coronavirus complications progressing to serious outcomes like ARDS, the need for artificial ventilation and intensive care,” said Oscar Groet, KD Pharma ’s Chief Executive Officer. Justin Slagel, SLA’s CEO, noted that he and his team are “leading the clinical development to expedite the trials in the various countries working closely with the respective regulatory authorities.” Groet continued, “This unique preparation has potential, to not only modify the COVID-19 disease process, reducing harmful, excess inflammatory responses, but to do so without suppressing the immune response to the virus which are vital to seroconversion giving the patient ongoing protection against continued viral challenge.”

Eligible patients with a positive COVID-19 test result will be able to participate in the trial and, after enrolment, will be given the product within a day of hospitalization and continue treatment for one month with a two-week follow-up. They will be monitored for progression to more serious outcomes and markers of inflammation, with the aim that EPAspire™ could help reduce the risk of mortality in severely ill patients.

EPAspire™ is a unique, novel oral formulation of highly purified eicosapentaenoic acid free fatty acid (EPA-FFA) in gastro-resistant capsules that is delivered to the gut at optimal pH allowing maximal absorption. EPAspire™ is currently in a clinical trial in Europe for the treatment of familial adenomatous polyposis (FAP). Proprietary data from the FAP trials suggests it suppresses expression of inflammatory cytokines believed to contribute to the progression of COVID-19 symptoms. Since the drug is currently in a Phase 3 trial for FAP in multiple countries, the companies have been able to initiate the COVID-19 trials very rapidly. The safety profile of EPAspire™ is well established from previous clinical studies.

The primary investigators in Italy who designed the protocol, believe EPA-FFA may change the course of SARS-CoV-2 infections by modulating immune response and protecting patients from its most severe complications. “EPA as a free fatty acid is very promptly absorbed and incorporated into the body’s phospholipid membranes, and then starts to act very quickly. Once incorporated into cell membranes, EPA-FFA significantly affects the production of pro-inflammatory mediators such as IL-6 and leukotriene B4 that play a crucial role in starting and maintaining the inflammatory process in the lungs. Moreover, EPA-FFA metabolism generates pro-resolving mediators and bioactive metabolites, that enhance innate microbial killing and organ protection,” they noted.

About KD Pharma Group

The KD Pharma Group SA is a contract manufacturer that develops products in the pharmaceutical and nutraceutical space. It is also one of the largest Omega-3 fatty acid producers in the world with 500 employees and a presence in the UK, Norway, Germany, Switzerland and the US. The KD Pharma Group employs state-of-the-art technology which is protected by numerous patents. Visit KDPharmaGroup.com to learn more.

About SLA Pharma

SLA Pharma AG is one of the few pharmaceutical companies in the world focused on developing medicines for the prevention and treatment of inflammatory, immune and gastrointestinal (GI) disorders such as, familial adenomatous polyposis (FAP), non-healing pilonidal sinus (PNS), anal fissures, inflammatory bowel disease and complications related to viral infections.

Contact information

Adam Ismail
Chief Strategy Officer
KD Pharma Group
+1 (385) 237-2787
adam.ismail@kdpharmagroup.com

Justin Slagel
Chief Executive Officer
SLA Pharma UK Ltd
+44 (0) 1923 681001
+44 (0) 7733 100400
jslagel@slapharma.com

About Business Wire

Business Wire
Business Wire



Subscribe to releases from Business Wire

Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.

Latest releases from Business Wire

Verimatrix Wins TV Technology’s Best of Show for VCAS 5 for DVB26.5.2020 17:45:00 CESTPress release

Verimatrix, (Euronext Paris: VMX), the leader in powering the modern connected world with people-centered security, today announced that its VCAS™ 5 for DVB solution is a winner of the 2020 Future Best of Show Awards, presented by TV Technology. The award recognizes VCAS 5 for DVB – a powerful, re-engineered version of its VCAS for DVB Broadcast security solution – as an outstanding new product. “Despite not being able to debut VCAS 5 for DVB at NAB Show, we are thrilled for it to receive such a positive reception by the industry experts who served on Future’s Best of Show Awards panel of judges,” commented Asaf Ashkenazi, COO of Verimatrix. “What makes the next-generation solution stand out is not just its ability to provide the highest level of broadcast security available today, but also its ability to do so while benefitting operators with improved speed, adaptability, scalability and cost savings – as well as a reliable end-user experience.” In April, Verimatrix announced it had f

Mary Kay Unveils Groundbreaking Research During Skin of Color Society Virtual Program26.5.2020 17:32:00 CESTPress release

Mary Kay Inc., a leader in skin care innovation for more than 56 years, continued its ongoing support of the beauty and scientific communities by presenting findings during the 2020 Skin of Color Society Symposium Virtual Program. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20200526005633/en/ Dr. Lucy Gildea, Chief Scientific Officer of Mary Kay (Photo: Mary Kay Inc.) Dr. Cristi Gomez, Director, Product Safety & Environmental Toxicology, revealed new research on the science behind LumiVie, an intensive serum by Mary Kay that brightens, energizes and moisturizes skin. As urbanization increases globally, the effects of pollution on skin is a growing concern. Chronic exposure to air pollution has been correlated with visible aging—in particular, the development of pigment spots. Researchers at Mary Kay developed a skincare formulation containing botanical extracts and vitamins B3 and C that is both suitable for sensitive skin

Jefferies to Hold Global Coronavirus Relief Charity Day Dedicated to the Memory of Peg Broadbent on May 27th26.5.2020 17:17:00 CESTPress release

Jefferies confirmed today that it will hold a Global Coronavirus Relief Charity Day tomorrow, Wednesday, May 27, 2020. The firm and its staff will contribute to global charities and relief efforts to assist those suffering from the devastation caused by the Coronavirus global pandemic and will offer investors around the world the opportunity to join these efforts by trading with Jefferies. Jefferies will dedicate this entire effort to their late CFO Peg Broadbent, who was a victim of this terrible disease. As previously announced, Jefferies will donate net commissions from trading on May 27 for all global trading in equities, fixed income and foreign exchange by the firm’s clients. In addition, Jefferies as a firm will donate $1 million directly, and all 3,822 employees worldwide will be given the opportunity to donate to these efforts. These contributions will be allocated to a series of charities on the front lines in fighting this ongoing global pandemic and providing urgently neede

New Automated Optical Inspection from Nordson EFD Verifies Fluid Deposit Placement and Accuracy26.5.2020 16:26:00 CESTPress release

Nordson EFD, a Nordson company (NASDAQ: NDSN), the world’s leading precision fluid dispensing systems manufacturer, introduces OptiSure™ Automated Optical Inspection (AOI) software and confocal laser as add-ons to its existing vision-guided dispensing robots. OptiSure AOI add-ons provide optical assurance of fluid deposit accuracy and integrate seamlessly with Nordson EFD’s proprietary DispenseMotion™ software. Using robots’ existing vision systems to verify fluid deposit widths and diameters, the AOI software determines if dispense requirements have been met. Constant closed-loop feedback provides automated quality control (QC) data, saving manufacturers time and cost. “Optical assurance of fluid deposit accuracy in an off-the-shelf solution is a game changer for our customers,” said Johnathan Titone, global product line manager for automated dispensing systems, Nordson EFD. “We saw a need in the market to integrate automated dispensing and AOI and we’re pleased to provide a market-le

LTI Wins 2020 SAP® Pinnacle Award as the Industry Innovation Partner of the Year26.5.2020 16:13:00 CESTPress release

Larsen & Toubro Infotech (BSE code: 540005, NSE: LTI), a global technology consulting and digital solutions company, has won the 2020 SAP® Pinnacle Award as the Industry Innovation Partner of the Year. This award recognizes LTI’s contribution to delivering best-in-class industry solutions that complement the industry portfolio from SAP. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20200526005562/en/ LTI has a long-term relationship with SAP, spanning over 20 years, and is uniquely positioned as a partner, co-Innovator and customer. LTI is a Global Strategic Services Partner, and this partnership enables its participation in the SAP S/4HANA® Movement program to promote and accelerate adoption of SAP S/4HANA. In addition, this partnership enables LTI to work closely with SAP’s industry teams to deliver transformational industry specific solutions such as its Intelligent Construction Enterprise. With its deep industry expertise

Rockwell Automation Issues 2019 Corporate Responsibility Report and Launches New Online Hub for Corporate Responsibility and Sustainability Content26.5.2020 16:00:00 CESTPress release

Rockwell Automation, Inc. (NYSE: ROK), today announced the launch of the annual Corporate Responsibility Report (CRR), highlighting the company’s efforts during 2019. The CRR reflects Rockwell Automation’s commitment to placing corporate responsibility and sustainability practices at the core of its approach to customers, employees, and communities. A global industrial automation and digital transformation leader, Rockwell Automation aims to be a principal voice in the corporate responsibility and sustainability space. The 2019 CRR highlights the company’s successful initiatives to continue to build a more inclusive workplace for employees; help customers reduce emissions and waste; and be a catalyst for progress in local communities. In conjunction with the publication of the 2019 CRR, Rockwell Automation today launched a new corporate responsibility content hub. Rockwell Automation’s corporate responsibility content hub will feature new stories and updates on its corporate responsibi

In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.

Visit our pressroom