Nichi GLOW: Japanese Beta-Glucan, in Children With Autism Spectrum Disorder, Improves Behavior, Sleep, and Gut Microbiome in a Clinical Study
In the first such report, children with Autism spectrum disorder (ASD) showed improvement in behaviour, learning skills and sleep, after oral consumption of AFO-202 strain of black yeast Aureobasidium Pullulans produced Beta 1,3 -1,6 glucan (Nichi GLOW), published in BMJ Neurology Open (http://dx.doi.org/10.1136/bmjno-2021-000203). Beneficial reconstitution of gut microbiota was also reported with Nichi GLOW, which is unique from other beta glucans by its source, production method, and purity.
This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20220313005031/en/
Improvement of learning and communication skills, sleep pattern and sleep quality beside peer interaction were the major changes observed in a clinical study after a 90-day consumption of Nichi GLOW beta glucan food supplement, according to the parents of study participants. One of them demonstrated his reading, writing and mathematical skills in a follow-up consulting with Dr Raghavan, developmental pediatrician & neurologist. ß-glucans considered clearing aggregated alpha-synuclein by enhancing NK cells & as a prebiotic, control enterobacteria, a cause of the disease, thus may have potentials in tackling neurological illnesses involving gut microbiome-dysbiosis. Nichi GLOW, a safe food supplement, which does not contain any allergens are worth larger clinical studies of longer follow-up in different populations to validate as an adjunct to conventional treatment in neurodevelopmental and neurodegenerative illnesses, as gut microbiota varies with food habits also, said Dr Raghavan. (Graphic: Business Wire)
Autism is a neurodevelopmental disorder affecting 1 in 44 children in the developed world, with multiple causes and varying severity of manifestation. These children are more likely to develop neurodegenerative diseases in later life. In the study, Nichi GLOW intake improved CARS score and communication skills (https://www.youtube.com/watch?v=reJOjBMKSg4). Nichi GLOW controlled enterobacteria, a gut microbiome producing harmful proteins like curli and amyloid, leading to Alpha-synuclein misfolding and aggregation in the neurons, a cause of the disease (https://doi.org/10.1101/2021.10.26.21265505). Synucleinopathy spreading through gut-brain-axis to the brain, might cause Parkinson’s or Dementia, therefore, it’s worth studying the prophylaxis of Nichi Glucan range of products in neurodegenerative conditions, as microglia activation is one of the mechanisms of their action in brain (https://doi.org/10.1016/j.jns.2021.117554), says Dr. Raghavan, the principal investigator.
The findings were presented in a webinar commemorating Autism Sunday (https://www.ncrmniche.org/autismsunday2022/proceedings/index.html), organized by Jesuit Antonyraj memorial Inter-disciplinary Center for Advanced Recovery and Education (JAICARE). Research conducted in Japan unraveled the hidden potentials (https://doi.org/10.1101/2021.08.05.21261640), of this ß-glucan; thanks to a wholesome ecosystem in Japan aiding development of novel solutions, which together with the trans-world inter-disciplinary network of healthcare expertise of GN Corp have made this path-breaking feat possible, commented the scientists. https://sponsored.bloomberg.com/article/jco/japan-where-high-tech-meets-high-value-foreign-direct-investment
Nichi Glucan range of products were approved as food additives in Japan in 1996 and don’t contain any commonly notified allergens. They are unique, being produced as an exo-polysaccharide by novel strains of Aureobasidium Pullulans in a GMP certified facility in Japan and exported in different brands: Nichi-GLOW, Neu-REFIX, Nichi Glucan & Nichi Glucan-REFIX; not intended to diagnose, treat, cure, or prevent any disease & approval status may vary between countries. Publications are meant for academic and research initiative purposes; not to be construed as medical advice. Physicians’ advice is recommended for specific health queries.
To view this piece of content from cts.businesswire.com, please give your consent at the top of this page.
Samuel JK Abraham
About Business Wire
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
Conviva Announces Streaming Audience Measurement Standard Leveraging Comprehensive, Continuous, Census-level Technology16.5.2022 20:21:00 CEST | Press release
Conviva, the Continuous Measurement Analytics platform for streaming media, today announces it will unveil a streaming audience measurement standard to be released for general availability at CES 2023. This expansion is in partnership with premium streaming providers using Conviva’s real-time cloud sessionization technology. The new standard provides census-level streaming audience ad packaging and measurement that is complimentary and interoperable with linear TV allowing streaming providers to compete at scale with the digital walled gardens solutions competing for ad budgets today. Conviva’s platform currently processes nearly 3 trillion streaming data events daily, supporting more than 500 million unique viewers watching 200 billion streams per year across 4 billion applications streaming on devices. “Audience measurement represents the streaming industry’s biggest opportunity and Conviva’s technology definitively unlocks its potential,” comments Keith Zubchevich, CEO of Conviva. “
Verimatrix Anti-Piracy and Threat Defense Experts To Highlight Latest Innovations at CABSAT and TT CS16.5.2022 17:45:00 CEST | Press release
Regulatory News: Verimatrix, (Euronext Paris: VMX), the leader in powering the modern connected world with people-centered security, today announced participation in two leading conferences this month: European Medical Device and Diagnostic Software Development and Compliance Conference (TT CS) – May 17-18 – Brussels, Belgium TT CS is Europe’s only dedicated conference for medtech cybersecurity professionals. Held at the Sheraton Brussels Airport Hotel, the event features two Verimatrix speakers. Nicole Lua, sales director, is scheduled to serve as moderator for a “Security By Design” roundtable at 1:35 p.m. on May 17. Neal Michie, director of product management, is scheduled to discuss the prevention of threats associated with unmanaged and quasi-managed devices during a session slated for 10:15-10:50 a.m. on May 18. CABSAT – May 17-19 – Dubai, UAE CABSAT is the most established and respected trade platform for broadcast, satellite, entertainment content & digital media sectors across
“Our Future is Light” Campaign Kicks off 2022 International Day of Light16.5.2022 17:03:00 CEST | Press release
An action-packed video styled as a blockbuster-movie trailer provides the linchpin for this year’s International Day of Light (IDL) campaign, “Our future is light. Play your part.” Released today, Day of Light features diverse characters successfully solving global-level problems using photonics-enabled technologies. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20220516005150/en/ Sponsored by SPIE, Optica, and IEEE Photonics Society, this year’s International Day of Light celebration showcases exciting, critical career opportunities in optics and photonics. (Graphic: Business Wire) Three professional societies – SPIE, the international society for optics and photonics, IEEE Photonics Society, and Optica, Advancing Optics & Photonics Worldwide – partnered to create the video and the accompanying 2022 IDL campaign. “Our future is light. Play your part” promotes the importance of light-based technologies and interesting careers
NielsenIQ Launches Retail Media Solution to Monetize Assets and Measure ROI for Retailers16.5.2022 16:01:00 CEST | Press release
Today, NielsenIQ, a global information services company, announced the launch of NielsenIQ Activate; a software-as-a-service (SaaS) solution that enables retailers to accelerate revenue opportunities through retail media and comprehensive customer insights that activate shoppers with personalized promotional offers. NielsenIQ Activate is comprised of dedicated applications for hyper-targeted audience building, offer and ads management, and end-to-end measurement. This SaaS tool, part of the NielsenIQ Connect platform, will allow retailers to create sustainable revenues by monetizing their retail media assets across physical and digital channels. Additionally, retailers will be able to boost credibility with brands and inform them of the insights they need to command their customers’ attention, act on those insights, and measure the ROI of their activities across all channels. “We are devoted to continuing our legacy by defining the next century of consumer and retail measurement,” says
TYLin and GPO Group Strategically Align16.5.2022 16:00:00 CEST | Press release
The GPO Group and Sam Schwartz, one of its operating companies, as part of a global effort to enhance connections and collaboration among companies in the Dar Group’s Global Infrastructure (GI) Pillar, are formally aligning with TYLin, the leading brand in the GI Pillar. The GPO Group and Sam Schwartz have added a TYLin “unifier” line to their names. Effective immediately, GPO will be known as GPO, A TYLin Company. Similarly, Sam Schwartz will be known as Sam Schwartz, A TYLin Company. The addition of the unifier line is part of a global strategic initiative to unify the companies in the Dar Group GI Pillar under the TYLin brand to provide more efficient access to its vast global resources and promote better collaboration among its staff. Aligning the two companies with TYLin — particularly in the rail and transit segments — means that GPO and Sam Schwartz, transportation and mobility leaders in Europe and the Americas, respectively, will expand their ability to deliver innovative thin
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.Visit our pressroom