NIH/NCI Grants Awarded to Inspirata and Case Western Reserve University Projects to Investigate Whole Slide Image Analysis to Predict the Aggressiveness of Certain Cancers
Multiple academic/industry grants and other funding totaling nearly $10M are being used to develop and validate digital pathology image-based risk predictors for breast, lung and head/neck cancers. If validated, the predictors will help identify which patients have a greater probability of cancer recurrence and a greater need for chemotherapy.
Vancouver, BC, March 20, 2018 (GLOBE NEWSWIRE) -- Cancer informatics and digital pathology workflow solution provider Inspirata®, Inc. announced today that it has been awarded a new National Institute of Health/National Cancer Institute (NIH/NCI) R01 grant with its academic partner, Case Western Reserve University (CWRU) in Cleveland, Ohio.
This grant will enable the multidisciplinary team of cancer researchers and physicians to develop and validate an image-based risk predictor of aggressiveness in head & neck cancers based on digitized H&E stained pathology images alone. This 5-year $3.15M Academic Industry Partnership (AIP) R01 grant is in addition to $6.4M in NIH/NCI R01 grants already awarded to Inspirata and CWRU over the last two years for developing digital pathology based assays for breast and lung cancers.
"In each of these cancers, we are looking at the shape, texture and spatial arrangement of the cell nuclei and mining the sub-visual image features from the digitized images of glass H&E stained pathology slides. The high-resolution digital whole slide images enable us to see differences in the cell structures in those individuals who have an early recurrence of cancer and those who have a late recurrence," says Principal Investigator, Dr. Anant Madabhushi, F. Alex Nason Professor II of Biomedical Engineering and founding director of the Center for Computational Imaging and Personalized Diagnostics (CCIPD) at the Case School of Engineering.
"Our teams have been able to leverage recent advances in digital pathology and computational image analysis methods to develop predictive and prognostic assays for a growing number of cancers," says Inspirata Executive Vice President and Founder, Mark Lloyd, PhD, MSM. "We are using these image-based assays to grade the aggressiveness of an individual's disease signature, which means that patients with less aggressive cancers can be spared more aggressive and expensive treatments like chemotherapy.
"The ramifications of this work are important globally as a more precise accessible and affordable option to traditional tests," continues Lloyd. "Once commercialized, our assays could offer patients the option to receive less expensive and less harmful therapies knowing that their risk is lower."
Other academic partners involved in the latest grant include Vanderbilt University's Dr. James S. Lewis Jr., MD, Co-PI, and Cleveland Clinic's Drs. Shlomo Koyfman and David Adelstein. Inspirata has licensed related technology to breast cancer prognosis and will be developing these image-based assays in conjunction with its quality management system and software production standards to create pre-commercial companion diagnostic tests. The company then plans to build a complete regulatory pathway for successful translation of the assays in the U.S. and abroad.
About Inspirata, Inc.
Inspirata®, Inc. offers the most comprehensive cancer diagnostics workflow solution available for precision diagnosis today. The solution, which employs a unique "solution-as-a-service" business and delivery model, accelerates anatomic and molecular pathology workflows and facilitates whole slide imaging and image analytics, prognostic and predictive assays, remote consultations and tumor boards. This comprehensive solution includes an Enterprise Service Bus (ESB) to help to solve interoperability issues and a Natural Language Processing Engine (NLP) for structuring data. Inspirata amalgamates this structured data into a central multi-institutional and multi-modal big data cancer repository for clinical, research and educational purposes. Its use will extend to physicians, patients, researchers and pharma among others. This comprehensive solution facilitates a modern precision diagnosis to build a strong foundation for precision medicine. For more information, please visit www.inspirata.com or contact email@example.com.
All trademarks used herein are the property of their respective owners.
A photo accompanying this announcement is available at http://www.globenewswire.com/NewsRoom/AttachmentNg/c01f9526-52ce-496f-b5d3-240c31a7c4c5
Marjorie Bulone Inspirata, Inc. 813-570-8905 firstname.lastname@example.org
The issuer of this announcement warrants that they are solely responsible for the content, accuracy and originality of the information contained therein.
Source: Inspirata, Inc. via Globenewswire
Följ NASDAQ OMX
Abonnera på våra pressmeddelanden.
Senaste pressmeddelandena från NASDAQ OMX
Brookfield Asset Management 2018 Second Quarter Results Conference Call And Webcast13.7.2018 16:04 | Pressmeddelande
Date: Thursday, August 9, 2018 Time: 11:00 a.m. (Eastern Time) TORONTO, July 13, 2018 (GLOBE NEWSWIRE) -- Second Quarter Conference Call You are invited to participate in Brookfield Asset Management's 2018 Second Quarter Conference Call & Webcast on Thursday, August 9, 2018 at 11:00 a.m. (Eastern Time) to discuss with members of senior management our results and current business initiatives. These results will be released on August 9th before 7:00 a.m. (Eastern Time) and will be available following the release on our website at www.brookfield.com "News - Press Releases." The Conference Call will also be Webcast live on our website, where it will be archived for future reference. To participate in the Conference Call, please dial (877) 255-3077 toll free in North America, or for overseas calls please dial (647) 252-4453 at approximately 10:50 a.m. The Conference Call will also be Webcast live at https://event.on24.com/wcc/r/1795914/64490BD29FBE43FAF176E3AF02943920. For those unable to p
NP3 och Diös gör bytesaffär i Gävle13.7.2018 12:15 | Pressmeddelande
NP3 och Diös gör en bytesaffär i Gävle. Syftet är att ytterligare stärka närvaron i respektive geografiska fokusområden. Diös köper 5 centrala samhällsfastigheter av NP3 och NP3 köper 13 industri- och bygghandelsfastigheter av Diös. Tillträde sker per den 3 september 2018. De 13 industri- och handelsfastigheter som NP3 förvärvar motsvarar en uthyrningsbar yta om cirka 80 000 kvadratmeter i områdena Näringen och Sörby Urfjäll. De största hyresgästerna är Ahlsells, Trelleborg och Swedol. Fastighetsvärdet uppgår till 345 mkr. De 5 samhällsfastigheterna Diös förvärvar motsvarar en total uthyrningsbar yta om 17 000 kvadratmeter, där den största fastigheten är en projektfastighet i närheten av Alderholmen, vilken kommer inrymma ett nytt kontor för Trafikverket. Tillträdet avseende den fastigheten sker under kvartal 1 2019. Övriga hyresgäster är Migrationsverket och två friskolor. Fastighetsvärdet uppgår till 300 mkr. Transaktionerna sker i bolagsform och kommer att redovisas under tredje kva
Squirrels Research Labs Announces Acorn Cryptocurrency Acceleration Hardware12.7.2018 21:04 | Pressmeddelande
NORTH CANTON, Ohio, July 12, 2018 (GLOBE NEWSWIRE) -- Squirrels Research Labs today announced Acorn, a new hardware component that improves efficiency and effectiveness of cryptocurrency mining. "We developed a piece of hardware called Acorn that increases the effectiveness of existing GPU mining operations without adding a significant cost," Squirrels president David Stanfill said. "This is a brand new concept that's never been done before." Acorn works in sync with GPUs to offload work that typically creates bottlenecks in mining. It performs the work much faster, resulting in an increase in overall mining efficiency. Initially three models will be available: CLE-101, CLE-215 and CLE-215+. Each model uses high-performance FPGA chips from Xilinx Inc. (NASDAQ:XLNX) in an M.2 slot to perform the least GPU-efficient parts of cryptocurrency mining. All Acorn models work with memory-intensive algorithms like Ethash and CryptoNight V1. The 215 and 215+ models work with both memory-intensive
NRT & Sightline Secure Multi-Year Exclusive Agreement with Ocean Resort Casino12.7.2018 19:30 | Pressmeddelande
Atlantic City's newest resort casino opens with a seamless customer experience for omni-channel solutions LAS VEGAS, July 12, 2018 (GLOBE NEWSWIRE) -- NRT Technology Corp. and Sightline Payments, LLC (together "NRT Sightline") today announced that Ocean Resort Casino in Atlantic City, N.J. opened its doors with the full suite of NRT Sightline solutions, including Play+, QJ self-serve kiosks, Cash+ ATM, credit and debit advances, VisuaLimits table signs and analytics, and the full suite of NCC credit and compliance solutions. "NRT Sightline has invested in cutting-edge technology that gives us a competitive advantage, and we look forward to our long-term partnership with this world-class technology leader," said Alan Greenstein, Chief Financial Officer of Ocean Resort Casino. "Ocean Resort Casino is Atlantic City's showcase property for a truly omni-channel guest experience. As the lines that separate cash and cashless commerce converge in gaming, our solutions remove friction from the
VeriTransfer(TM) Unveils the First Known Proof-of-Concept for a Blockchain Enabled Firearms Licence Verification and Ownership Transfer12.7.2018 17:43 | Pressmeddelande
Blockchain Enabled Firearms Solution Ensures Instant Verification of Ownership and Safe Transfer While Maintaining Data Privacy TORONTO, July 12, 2018 (GLOBE NEWSWIRE) -- VeriTransfer(TM) today announced the completion of its Proof-of-Concept ("POC") of the first publicly announced Blockchain enabled solution that decentralizes the process of storing the ownership rights and transfer of firearms. VeriTransfer(TM) is also pleased to announce that it will donate a percentage of all future revenues or the proceeds from any future sale of the company towards foundations whose mission is to end gun violence and build safer communities. The Gun Epidemic & The Economic Impact The United States hosts 4.4% of the world's population, but almost 50% of the 644 million civilian-owned guns globally are located in the U.S. Disturbingly, more American citizens have died as a result of gunshots in the U.S. since 1968 than on the battlefield of all the wars in American history from 1175 to 2015. In add
Nordens första gröna strukturerade placering noteras på Nasdaq Stockholm12.7.2018 13:15 | Pressmeddelande
STOCKHOLM, Sweden, July 12, 2018 (GLOBE NEWSWIRE) -- Imorgon, den 13 juli, noteras en publikt distribuerad strukturerad placering baserad på en grön obligation på Nasdaq Stockholm. Det är den första i sitt slag i Norden. Placeringen emitteras av den franska banken Crédit Agricole CIB och distribueras av Garantum Fondkommission, en ledande nordisk leverantör av strukturerade placeringar. Garantum har alltid varit en pionjär inom strukturerade placeringar, men det är inte varje dag vi får möjligheten att bryta ny mark på ett så viktigt område som grön finans, säger Mikael Axelsson, VD på Garantum Fondkommission. Vår mission är att skapa rätt placering vid rätt tillfälle och få saker kan vara mer rätt än en investering som ger positiva effekter på samhälle och miljö. Vi ser fram emot att fortsätta utnyttja flexibiliteten i strukturerade placeringar för att erbjuda varierad hållbar exponering på ett effektivt sätt. Och även om det alltid är kul att var först ut med något betydelsefullt, så
I vårt pressrum kan du läsa de senaste pressmeddelandena, få tillgång till pressmaterial och hitta kontaktinformation.Besök vårt pressrum