Business Wire

Novel Blood Pressure Stabilization Therapy Presented at Neuroscience 2021

Share

ONWARD Medical N.V. (Euronext: ONWD), a medical technology company creating innovative therapies to restore movement, independence, and health in people with spinal cord injury, today announced Grégoire Courtine, Ph.D., Professor of Neuroscience at the Swiss Federal Institute of Technology (EPFL) and co-Director of NeuroRestore, demonstrated the effectiveness of ONWARD’s ARCTherapy to stabilize blood pressure after spinal cord injury during his Presidential Special Lecture at NEUROSCIENCE 2021.

“Paralysis and loss of sensation are the more commonly known impacts of spinal cord injury, but a potentially more serious complication is orthostatic hypotension - low blood pressure tied to changes in body position,” said Professor Courtine. “We were excited to demonstrate and discuss how this new approach may provide a viable and important therapy for people with spinal cord injury.”

This novel therapy is currently being investigated in the STIMO HEMO study, building on a discovery first published in Nature that identifies the low thoracic spinal cord as a hemodynamic “hotspot”, which when stimulated via a proprietary algorithm called ARC Therapy, has the potential to restore blood pressure stability after spinal cord injury. ONWARD is developing and commercializing this therapy, leveraging its investigational ARCIM implantable device platform.

During his Presidential Special Lecture, Professor Courtine showed how stimulation of the hemodynamic hotspot elevated blood pressure in one of the STIMO HEMO participants. A video of that portion of the lecture can be viewed here.

More information about ONWARD’s investigational ARC Therapy can be found in this video.

About ONWARD

ONWARD Medical, N.V. (@onwdempowered) is a medical technology company creating innovative therapies to restore movement, independence, and health in people with spinal cord injury. ONWARD’s work builds on more than a decade of basic science and preclinical research conducted at the world’s leading neuroscience laboratories. ONWARD’s ARC Therapy, which can be delivered by implantable (ARCIM) or external (ARCEX) systems, is designed to deliver targeted, programmed stimulation of the spinal cord to restore movement and other functions in people with spinal cord injury, ultimately improving their quality of life. ONWARD has received three Breakthrough Device Designations from the FDA encompassing both ARCIM and ARCEX. The company’s first FDA pivotal trial for the ARCEX device, called Up-LIFT, commenced in January 2021 with plans to enroll 65 subjects at up to 15 centers worldwide.

ONWARD is headquartered at the High Tech Campus in Eindhoven, the Netherlands and the EPFL Innovation Park in Lausanne, Switzerland, with a growing U.S. presence in Boston, Massachusetts, USA. For additional information about the company, please visit ONWD.com and follow us on Twitter and LinkedIn.

Disclaimer

Certain statements, beliefs and opinions in this press release are forward-looking, which reflect the Company or, as appropriate, the Company directors’ current expectations and projections about future events. By their nature, forward-looking statements involve a number of risks, uncertainties and assumptions that could cause actual results or events to differ materially from those expressed or implied by the forward-looking statements. These risks, uncertainties and assumptions could adversely affect the outcome and financial effects of the plans and events described herein. A multitude of factors including, but not limited to, changes in demand, competition and technology, can cause actual events, performance or results to differ significantly from any anticipated development. Forward looking statements contained in this press release regarding past trends or activities should not be taken as a representation that such trends or activities will continue in the future. As a result, the Company expressly disclaims any obligation or undertaking to release any update or revisions to any forward-looking statements in this press release as a result of any change in expectations or any change in events, conditions, assumptions or circumstances on which these forward-looking statements are based. Neither the Company nor its advisers or representatives nor any of its subsidiary undertakings or any such person’s officers or employees guarantees that the assumptions underlying such forward-looking statements are free from errors nor does either accept any responsibility for the future accuracy of the forward-looking statements contained in this press release or the actual occurrence of the forecasted developments. You should not place undue reliance on forward-looking statements, which speak only as of the date of this press release.

To view this piece of content from cts.businesswire.com, please give your consent at the top of this page.

Contact information

For general inquiries:
info@onwd.com

For media inquiries:
Bryan Gibbs, Finn Partners
bryan.gibbs@finnpartners.com
+19737134709

For European Media and Investor Enquiries:
Gunther De Backer, Backstage Communication
gunther@backstagecom.be
Tel: +32 (0)475 903 909

About Business Wire

Business Wire
Business Wire



Subscribe to releases from Business Wire

Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.

Latest releases from Business Wire

NTHU: A Model of Sustainability2.12.2021 11:00:00 CET | Press release

National Tsing Hua University (NTHU) was awarded the Taiwan University Sustainability Award at the 14th Taiwan Corporate Sustainability Awards (TCSA) held by the Taiwan Institute for Sustainable Energy (TAISE) on November 17. Standing out amongst the 38 participating universities, NTHU was ranked first in the comprehensive evaluation, and in the individual competitions also received the Social Inclusion Leadership Award and the University Sustainability Report Gold Award. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20211202005031/en/ National Tsing Hua University was awarded the Taiwan University Sustainability Award. President Hocheng Hong (center) and Chief Sustainability Officer Tai Nyan-hwa (second from the left), Sustainability Office Director Lin Fu-ren (first from the left), Vice President and Chief of Staff King Chung-Ta (second from the right), Dean of International College Doong Ruey-an (first from the right). (Ph

Honor to Knight! DRAG S/X PnP-X Kit Is Launched2.12.2021 10:35:00 CET | Press release

In November, VOOPOO announced the overseas launch of the DRAG S/X PnP-X KIT. The product carries out comprehensive technical upgrading on the basis of DRAG S/X, endows the core concept of "Chivalry" in product design, and pays tribute to the glory and virtue of knights. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20211202005381/en/ (Photo: Business Wire) Originated from the spirit of martial arts of German in the Middle Ages, the spirit of chivalry was then embodied in soldiers of the European battlefield in the 11th century, and guards of emperors and warriors of Christ. Nowadays, chivalry is culturally continued and nobly expressed as gentleman demeanor. Despite passage of time, the only constant is the faith that knight loyally holds and eight virtues of knights flowing in their blood. After learning about this legendary medieval history and digging out the core of chivalry, VOOPOO design and R&D personnel were deeply to

Zilliant Announces Significant Growth in Europe2.12.2021 09:30:00 CET | Press release

Zilliant, the industry leader in intelligent B2B price optimization, price management and sales guidance software, today announced significant growth in Europe, marked by compound annual revenue growth of 55% from 2018-2021 as well as significant growth of new customers. “B2B company leaders are increasingly seeking alternatives to the traditional means of managing prices and enabling sales teams,” said Zilliant President and Chief Executive Officer Greg Peters. “Tying strategy to effective execution can be even more difficult for companies in Europe, particularly in global, multi-country businesses. Our growth in the region can be attributed to the increased breadth of our product portfolio, addressing the full spectrum of pricing challenges in B2B, and our passion for powering intelligent commerce for our customers.” Zilliant maintains offices in Paris, London, Milan, Italy, and Walldorf, Germany. In recent years, a wide variety of B2B companies in Europe with worldwide operations ha

Hopp Secures $2.8 Million Funding From Brunnur Ventures to Build a Global Sustainable Micromobility Sharing Franchise2.12.2021 09:27:00 CET | Press release

Hopp (www.hopp.bike),the sustainable electric scooter rental company, is pleased to announce an investment by Brunnur Ventures of $2.8 million into the company to drive international growth of its worldwide franchise strategy. Hopp is the sustainable transportation solution for the world’s modern city enabling riders to travel without leaving a carbon footprint. Hopp's primary mission is to leave behind a cleaner planet, one ride at a time, with all parts of the business carbon negative. Hopp is uniquely focused on smaller cities, local travel and smaller fleets – an almost untouched market as more than 95% of cities in Europe with less than 500,000 inhabitants are currently unserved. “Our goal is to influence the electric scooter market in the same way as McDonald’s for the hamburger,” commented CEO Eythór Steinarsson. “We want to bring this technology to smaller cities where there is a big opportunity and to get locals to work with us. We want to bring the sharing economy to the way

Bitcoin Capital Expands its Crypto Asset Offering2.12.2021 09:11:00 CET | Press release

Bitcoin Capital announced today that it has again listed two world firsts on the SIX Swiss Exchange. With 1 FiCAS Active Bitcoin ETP and 1 FiCAS Active Ethereum ETP, the company has launched two products actively managed by the highly experienced crypto asset manager FICAS AG. With active management, the products aim to counter negative price fluctuations and therefore outperform the two largest cryptocurrencies by capitalization. With the listing, institutional, professional, and private investors in Switzerland, Liechtenstein, and the European Union (excluding Hungary) can easily invest in the new products via their bank or broker, just as they do with other listed financial investments such as equities or bonds. "Our purpose is to grant investors safe and easy access to digital assets and are convinced that crypto assets will soon be part of the diversification strategy of many investment portfolios. The two new products with the most relevant cryptocurrencies as underlying may, thr

Ricardo Announces Approved Science-based Targets as We Advance Towards Net Zero2.12.2021 09:00:00 CET | Press release

Ricardo, a world-class environmental, engineering and strategic-consulting company, is pleased to announce that our proposed greenhouse gas emissions reduction targets have been approved by the Science Based Targets initiative (SBTi) and that they are in line with the goals set forth in the 2015 Paris Agreement. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20211202005044/en/ Ricardo is pleased to announce that proposed greenhouse gas emissions reduction targets have been approved by the Science Based Targets initiative (Graphic: Business Wire) The Science Based Targets initiative (SBTi) is a collaboration between the CDP, the United Nations Global Compact, World Resources Institute (WRI) and the World Wide Fund for Nature (WWF). We now join a growing group of global businesses that have received approval of their targets, ensuring that greenhouse gas emissions from Ricardo’s operations (scopes 1 and 2)1 are consistent with t

CSC Global Financial Markets Expands its Depositary Services in the Netherlands with New Licenses for UCITS; Alternative Funds License Broadened2.12.2021 09:00:00 CET | Press release

CSC, the world’s leading provider of business, legal, tax, and digital brand services, has secured extra depositary licenses from the Netherlands Authority Financial Markets (AFM). After being one of the first nonbank depositaries to receive a depositary license for real estate and infrastructure funds, CSC has now extended its license to include undertakings collective investment in transferable securities (UCITS) funds. In addition, CSC’s alternative funds license has been extended to include the following asset classes—financial instruments, private equity, private debt, and shipping. “We’re delighted that our depositary services now cover an extensive list of investment strategies in the Netherlands. The addition of UCITS funds license is a major milestone in the history of CSC in the Netherlands. The market response is extremely positive and we are already onboarding our first UCITS fund manager,” says Mascha Hartskeerl, head of depositary services for CSC Global Financial Markets

In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.

Visit our pressroom