ProteinQure Collaborates with AstraZeneca to Design Novel Peptide Therapeutics
ProteinQure, a leader in computational protein drug discovery, announces a collaboration with the global biopharmaceutical company AstraZeneca to apply structure-based design to the creation of therapeutic libraries with the aim of accelerating the research and development of peptide therapeutics.
Peptide therapeutics have unique properties that make them highly effective against some disease targets outside the scope of traditional small molecule and antibody modalities. However, due to the number of peptide variations, very few of these potential therapeutics have been studied. Integrating high-accuracy biophysical models and machine learning, it is possible to explore this vast therapeutic space and design peptide libraries with broad applicability in drug discovery.
The collaboration will leverage ProteinQure's expertise in computational methods and structure-based drug design. AstraZeneca will conduct experimental validation, drawing on the company’s extensive expertise in biologics.
"We are excited to collaborate with AstraZeneca to demonstrate the application of our technology on a large scale. By combining ProteinQure's proprietary computational tools with AstraZeneca’s ability to refine and validate millions of therapeutic candidates in high-throughput, we can rapidly determine therapeutic leads outside the scope of conventional synthetic antibody libraries. State-of-the-art computational tools have not been fully explored in biologics R&D and we are excited to partner with AstraZeneca with the aim of discovering novel therapeutic leads for some of the most challenging drug targets faced by the industry," said Chris Ing, CSO, ProteinQure.
"The combination of designed peptide libraries, based on ProteinQure’s computational methods, with our advanced capabilities in display technologies will help us harness the potential of this therapeutic class. AstraZeneca continues to collaborate with cutting-edge companies in our ambition to discover novel treatments and increase the speed at which we can bring treatments to patients," said Tristan Vaughan, Vice President Antibody Discovery & Protein Engineering, R&D, AstraZeneca.
About ProteinQure Inc.
ProteinQure is a computational drug discovery platform for protein-based pharmaceuticals. Their platform combines quantum computing, machine learning and molecular dynamics simulations to help refine and optimize protein therapeutics. These techniques are less reliant on data than other computational approaches and have the potential to explore new therapeutic space. ProteinQure collaborates with its partners to help design the drugs of tomorrow. ProteinQure is headquartered in Toronto, Canada. For more information please visit www.proteinqure.com.
About Business Wire
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
CStone, Pfizer Enter into Strategic Collaboration to Address Oncological Needs in China30.9.2020 05:22:00 CEST | Press release
CStone Pharmaceuticals (“CStone”, HKEX: 2616)] and Pfizer Investment Co. Ltd. ("Pfizer Investment") and Pfizer Corporation Hong Kong Limited ("Pfizer Hong Kong") (both of which are subsidiaries of Pfizer Inc. (NYSE: PFE)) announced today the formation of a strategic collaboration that encompasses a $200 million equity investment by Pfizer Hong Kong in CStone, collaboration between CStone and Pfizer Investment for the development and commercialization of CStone’s sugemalimab (CS1001, PD-L1 antibody) in mainland China, and a framework between CStone and Pfizer Investment to bring additional oncology assets to the Greater China market. This collaboration provides financing to support CStone’s development of sugemalimab, a potential best-in-class PD-L1 antibody that is being developed for high-incidence cancer indications in China, including lung, gastric and esophageal cancers, among others. Pfizer will in-license and exclusively lead commercialization of sugemalimab in China, harnessing
Harm Reduction Policies Essential to Prevent Cancer, Say I-Com and MEPs30.9.2020 05:01:00 CEST | Press release
I-Com, the Institute for Competitiveness, yesterday hosted a landmark roundtable in the context of Europe’s Beating Cancer Plan, summarised here, bringing together policymakers from across the political spectrum, academics and scientists to present the findings of their study on best practices to beat cancer. During the roundtable, the discussion analysed best practices and successes of harm reduction policies across Europe. Enabling citizens to live healthier lifestyles by making less risky products accessible, such as vaping devices for smokers, by conducting education and awareness campaigns about responsible alcohol consumption and by building infrastructure promoting physical activity are examples of the core ideas driving the evidence-based approach behind harm reduction policy. During the public consultations on the Beating Cancer Plan, 20% of submissions highlighted harm reduction’s potential role. Dolors Montserrat, Hosting MEP and a member of the Special Cancer Committee, sai
“Japanese Cuisine and Food Culture Human Resource Development Program 2020” (Tokyo Japan) Now Accepting Applications for Online Participants30.9.2020 05:00:00 CEST | Press release
Applications are now being accepted for a training program on Japanese cuisine for non-Japanese chefs who are serious about studying Japanese cuisine, officially supported by the Ministry of Agriculture, Forestry and Fisheries (MAFF) of Japan. We are now accepting applications for an online training program to acquire correct knowledge and skills in Japanese cuisine and food culture. Study under a curriculum taught by first-class chefs in your own country. It’s a great opportunity to learn techniques in authentic Japanese cuisine and obtain official certification by the Japanese government in a short period of time. Application Deadline: Oct. 30, 2020 E-learning Course: Oct. 19 - Nov. 30, 2020 Real-time Online Course (selected participants only): Dec. 1, 2020 - Feb. 28, 2021 (Dates are Japan standard time) Participate by watching videos of top chefs*1 supervised by the Japanese Culinary Academy*2 free of charge! Study the fundamentals of Japanese cuisine via videos and textbooks. Durin
Velodyne Lidar, Inc. and Graf Industrial Corp. Announce Closing of Business Combination29.9.2020 22:01:00 CEST | Press release
Velodyne Lidar, Inc. (“Velodyne”) and Graf Industrial Corp. (“Graf”) jointly announced today that they have closed their previously announced business combination, pursuant to which Velodyne became a wholly owned subsidiary of Graf and Graf changed its name to Velodyne Lidar, Inc. The business combination was approved at a special meeting of Graf’s stockholders held today. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20200929006064/en/ Beginning on Wednesday, September 30, 2020, the common stock and warrants of Velodyne Lidar, Inc., the post-combination company, are expected to begin trading on The Nasdaq Global Select Market under the ticker symbols “VLDR” and “VLDRW,” respectively. Graf’s units, common stock and warrants will cease trading on the New York Stock Exchange today. About Velodyne Lidar, Inc. Velodyne Lidar is a global leader in lidar technology providing real-time 3D vision for autonomous systems thereby empowe
PMI to Address Equality & Transformation During Upcoming International Events29.9.2020 16:22:00 CEST | Press release
Philip Morris International Inc. (PMI) (NYSE: PM) today announced its participation in several global forums focused on equality in the workplace. Members of PMI’s Senior Management Team—including Chief Diversity Officer Silke Muenster—will detail the steps PMI is taking to further diversify its workplace and explain how fostering a culture built on broader perspectives increases creativity and productivity, ultimately driving innovation and consumer-centricity. Events include: - Sept. 30: Marian Salzman, senior vice president, global communications, will address The Hill’shttps://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fthehill.com%2Fevent%2F517572-century-of-the-woman&esheet=52297021&newsitemid=20200929005799&lan=en-US&anchor=%26%238220%3BCentury+of+the+Woman%2C%26%238221%3B&index=2&md5=dd59f1acaf064094c36e98292381df3c “Century of the Woman,” anevent bringing together remarkable women leaders and decision-makers to discuss progress toward equality and the barriers th
SMITHS DETECTION INTRODUCES COMPACT X-RAY SCANNER FOR VERSATILE COMMERCIAL SECURITY APPLICATIONS29.9.2020 16:00:00 CEST | Press release
Smiths Detection announces its newest X-ray inspection system, HI-SCAN 5030C, that addresses a critical gap in commercial security screening solutions with its optimal size, durability and mobility. Combined with a market-leading HiTraX 3 electronic platform for superior image quality, the HI-SCAN 5030C is specifically designed to enhance security screening operations from courthouses to corporate campuses. Its compact size and lightweight construction enable it to fit seamlessly into checkpoints and mailrooms. Vibration absorbers make it possible to transport HI-SCAN 5030C between various locations without requiring re-calibration, providing maximum flexibility. The HI-SCAN 5030C is Smiths Detection’s smallest X-ray inspection system and offers a wide variety of options including stainless steel castors, storage compartment, 24” monitor, newly designed keyboard with image manipulation keys, and foldable input/output conveyors. It can be upgraded with add-on software packages for train
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.Visit our pressroom