XBiotech Publishes Results in PLOS ONE for its True Human Antibody 514G3 Targeting S. aureus
Report Documents 514G3's Ability to Protect Mice Against Deadly S. aureus Bacteremia Infections
AUSTIN, Texas, Jan. 25, 2018 (GLOBE NEWSWIRE) -- XBiotech Inc. (NASDAQ:XBIT) announced today the publication of "A Natural Human Monoclonal Antibody Targeting Staphylococcus Protein A Protects Against Staphylococcus aureus (S. aureus) Bacteremia ." in the journal PLOS ONE. The article reports on research involving the Company's therapeutic monoclonal antibody, 514G3, and its ability to neutralize a key immune evasion mechanism of S. aureus involved in the establishment of serious or even deadly infections. The 514G3 antibody was a naturally occurring antibody derived from a healthy individual with highly targeted immunity against S. aureus capable of neutralizing all strains of the bacteria, including a drug-resistant or so-called MRSA form.
"Continued emergence of multi drug resistant strains of S. aureus along with increased aging and immunocompromised populations, contribute to a need for new solutions to this deadly infection," commented Dr. Sushma Shivaswamy, Ph.D., XBiotech's Chief Scientific Officer. She further stated, "The present study confirms the mechanism of action of 514G3, and its ability to neutralize and kill the bacteria in a strain-independent manner."
The Company has previously announced top-line results from a Phase I/II clinical study, which reported a reduction in adverse events and shorter hospitalization associated with the 514G3 therapy, even with 514G3-treated patients tending to be sicker than those receiving placebo. The U.S. FDA has recognized the potential of this treatment, designating this as a Fast Track development program.
About True Human(TM) Therapeutic Antibodies
XBiotech's True Human(TM) antibodies are derived without modification from individuals who possess natural immunity to certain diseases. With discovery and clinical programs across multiple disease areas, XBiotech's True Human antibodies have the potential to harness the body's natural immunity to fight disease with increased safety, efficacy and tolerability.
XBiotech is a fully integrated global biosciences company dedicated to pioneering the discovery, development and commercialization of therapeutic antibodies based on its True Human(TM) proprietary technology. XBiotech currently is advancing a robust pipeline of antibody therapies to redefine the standards of care in oncology, inflammatory conditions and infectious diseases. Headquartered in Austin, Texas, XBiotech also is leading the development of innovative biotech manufacturing technologies designed to more rapidly, cost-effectively and flexibly produce new therapies urgently needed by patients worldwide. For more information, visit www.xbiotech.com.
Cautionary Note on Forward-Looking Statements
This press release contains forward-looking statements, including declarations regarding management's beliefs and expectations that involve substantial risks and uncertainties. In some cases, you can identify forward-looking statements by terminology such as "may," "will," "should," "would," "could," "expects," "plans," "contemplate," "anticipates," "believes," "estimates," "predicts," "projects," "intend" or "continue" or the negative of such terms or other comparable terminology, although not all forward-looking statements contain these identifying words. Forward-looking statements are subject to inherent risks and uncertainties in predicting future results and conditions that could cause the actual results to differ materially from those projected in these forward-looking statements. These risks and uncertainties are subject to the disclosures set forth in the "Risk Factors" section of certain of our SEC filings. Forward-looking statements are not guarantees of future performance, and our actual results of operations, financial condition and liquidity, and the development of the industry in which we operate, may differ materially from the forward-looking statements contained in this press release. Any forward-looking statements that we make in this press release speak only as of the date of this press release. We assume no obligation to update our forward-looking statements whether as a result of new information, future events or otherwise, after the date of this press release.
The issuer of this announcement warrants that they are solely responsible for the content, accuracy and originality of the information contained therein.
Source: XBiotech, Inc via Globenewswire
Följ NASDAQ OMX
Abonnera på våra pressmeddelanden.
Senaste pressmeddelandena från NASDAQ OMX
Medibio Corporate Health Extends Global Footprint Signing Contract with Jacobs Engineering25.5.2018 16:38 | Pressmeddelande
Jacobs, one of the world's largest engineering and environmental consultancy groups, has more than 70,000 employees globally SYDNEY, Australia and MINNEAPOLIS, May 25, 2018 (GLOBE NEWSWIRE) -- Medibio Limited (MEB or the Company) (ASX:MEB) (OTCQB:MDBIF), a mental health technology company, today announced a significant contract for Medibio's Corporate Health product with Dallas, TX-based Jacobs Engineering across their Asia Pacific, Middle East, and European divisions. Through the Mental Health Check-In, companies can offer employees an end-to-end mental health program, direct to their devices, to see how the mind and body are tracking. It's a personalized, private, and objective way to see the unseeable: mental health issues in the workplace. Employees are provided the opportunity to confidentially check-in on their mental health and receive personalized confidential results from both an objective biometric screening in conjunction with a 12-minute subjective survey. Employers receive
LeoVegas warms up ahead of FIFA World Cup with launch of sportsbook 2.0 and new design25.5.2018 14:20 | Pressmeddelande
LeoVegas is conducting constant development to further improve the gaming experience with the launch of sportsbook 2.0 and a new design for Leovegas.com. It strengthens LeoVegas mobile position and increases the competitiveness within sports betting. "Our new design has been created to give our customers a better overview of all games in all product verticals," comments Gustaf Hagman, CEO of LeoVegas. "The design features a simplified and more intuitive experience, which is especially important in sport, where relevance and simplicity are key factors. On top of this we are launching a number of updates and expanding ownership of the sportsbook. Together this builds further on creating a world class gaming experience and is in line with our passion "Leading the way into the mobile future". This will give us the right conditions ahead of the World Cup, but it also represents a long-term springboard towards building the world's best mobile sportsbook". Improved sports betting experience L
LeoVegas värmer upp inför fotbolls VM och lanserar sportbok 2.0 med ny design25.5.2018 14:19 | Pressmeddelande
Det sker en ständig utveckling av LeoVegas och för att förbättra spelupplevelsen ytterligare lanseras nu sportbok 2.0 samt en ny design av LeoVegas.com. Det stärker LeoVegas mobila position och ökar konkurrenskraften inom sportsbetting. "Vår nya design är skapad för att ge våra kunder en bättre överblick för alla spel inom samtliga produktvertikaler. Designen ger en förenklad och mer intuitiv upplevelse vilket är särskilt viktigt inom sport där relevans och enkelhet är nyckelfaktorer. Utöver det lanserar vi ett flertal uppdateringar samt ökar ägarskapet av sportboken. Tillsammans bygger det vidare på att skapa en spelupplevelse i världsklass och går i linje med vår passion "Leading the way to the mobile future". Detta ger oss rätt förutsättningar inför VM men de är också ett långsiktigt avstamp till att bygga världens bästa mobila sportbok. säger Gustaf Hagman, CEO LeoVegas. Förbättrad sportupplevelse LeoVegas har nu ägarskap över flera sidor som leverantören Kambi tidigare hade kontro
VIRGIN PULSE ANNOUNCES INDUSTRY-LEADING GDPR COMPLIANCE25.5.2018 14:00 | Pressmeddelande
Virgin Pulse Extends the GDPR's Strong Data Privacy Rights to All Clients and Members Across the Globe PROVIDENCE, R.I., May 25, 2018 (GLOBE NEWSWIRE) -- Virgin Pulse, the leading global provider of digital employee health, wellbeing and engagement solutions, today announced that it has achieved compliance with the EU General Data Protection Regulation (GDPR) for the Virgin Pulse platform. The company has also appointed Associate Counsel Beatrice Botti as Data Protection Officer (DPO) to oversee the Virgin Pulse privacy program. With this achievement, Virgin Pulse leads the market as the first company in the wellbeing and engagement industry to fully meet the comprehensive standards of the new GDPR data privacy law. The company has completed a thorough review of its internal data collection, storage and handling processes and implemented enhancements to achieve GDPR compliance and give all Virgin Pulse customers and members greater control over their personal data. The GDPR is the firs
Resverlogix Provides Unrestricted Educational Grant for Epigenetic Symposium at International Renal Congress25.5.2018 07:45 | Pressmeddelande
CALGARY, Alberta, May 24, 2018 (GLOBE NEWSWIRE) -- Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) today announced that on Friday, May 25, 2018, at the European Renal Association - European Dialysis and Transplant Association (ERA-EDTA) Congress in Copenhagen, Denmark, the Company is supporting a symposium titled: "Epigenetics in CKD & CVD: A potential breakthrough therapy?" The symposium highlights the role of epigenetics and BET-inhibition in chronic kidney disease and cardiovascular disease, especially in patients with diabetes mellitus, and the significant unmet need that still exists in this patient population. The symposium is co-chaired by Vincent M. Brandenburg, MD - Nephrologist, Aachen, Germany and Kamyar Kalantar-Zadeh, MD - UC Irvine School of Medicine, Irvine, CA, USA, both leading scientists also serving as advisors to Resverlogix's Renal program. The speakers and agenda are as follows: Introduction Vincent M. Brandenburg, MD - University Hospital of the RWTH
Atico Reports Consolidated Financial Results for the First Quarter of 201824.5.2018 22:30 | Pressmeddelande
(All amounts expressed in US dollars, unless otherwise stated) VANCOUVER, British Columbia, May 24, 2018 (GLOBE NEWSWIRE) -- Atico Mining Corporation (the "Company" or "Atico") (TSX.V:ATY) (OTC:ATCMF) today announced its financial results for the three months ended March 31, 2018, posting a net income of $0.4 million. Fernando E. Ganoza, CEO and Director, commented, "The strong production and all-in sustaining cash cost of $1.85 achieved this quarter is not reflected in the financial results as a large concentrate shipment was delayed to the second quarter, along with the revenue associated with those tonnes. The shipping schedule is expected to stabilize during the second quarter, where we will then benefit from the additional shipped concentrate and recognized revenue. We anticipate strong financial results in the next quarter." Mr. Ganoza continued, "Our emphasis will continue to be on further strengthening our balance sheet, improving production costs and most importantly regional
I vårt pressrum kan du läsa de senaste pressmeddelandena, få tillgång till pressmaterial och hitta kontaktinformation.Besök vårt pressrum