Asahi Kasei Providing Samples of Hyaluronic Acid Nanogel as a New Pharmaceutical Excipient
Asahi Kasei has established industrial manufacturing technology for hyaluronic acid (HA) nanogel* as a new pharmaceutical excipient, and is providing samples to prospective customers in order to commercialize the product.
This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20200804005334/en/
Chemical structure and self-assembly of HA nanogel (Graphic: Business Wire)
The Functional Additives Division of Asahi Kasei’s Specialty Solutions SBU supplies Ceolus™ microcrystalline cellulose to pharmaceutical manufacturers around the world for use as an excipient for drug tablets. The commercialization of HA nanogel would expand the product lineup by adding a drug delivery system (DDS) base material for injection formulations.
HA nanogel is expected to improve the quality of life (QOL) for patients by enabling the low-toxicity solubilization of insoluble drugs, facilitating the formulation of biopharmaceuticals such as proteins and peptides by suppressing their aggregation and denaturation, and reducing the frequency of injection when repeated administration is required.
Characteristics of the new HA nanogel:
HA nanogel is derived by the partial modification of hyaluronic acid with cholesterol. In water, self-association occurs among the cholesterol portions due to hydrophobic interaction, causing the formation of nanometer-scale hydrogel. The physical properties of HA nanogel depend on the molecular weight of HA and the cholesterol modification rate. Two grades of samples, a dispersion grade and a precipitation grade, are currently available.
The hydrophobic interaction enables a wide variety of insoluble drugs, ranging from low and medium molecular weight (MW) compounds to proteins, to be enclosed in the nanogel by simple mixing. This makes HA nanogel suitable for use as a base material for DDS. The main functions are sustained release, solubilization, suppression of aggregation, and retention of drug activity. Grades can be optimized to match specific customer requirements.
Asahi Kasei will make a formal decision on the commercialization of HA nanogel after confirming that the provided samples have contributed to solutions for the development of drug formulations by customers.
Asahi Kasei remains committed to meeting the needs of customers through products that contribute to life and living for people around the world.
Inquiries regarding HA nanogel samples should be directed to:
New Product Development Office
Functional Additives Division
Specialty Solutions SBU
Asahi Kasei Corp.
* Asahi Kasei has an exclusive license for HA nanogel technology developed by Chugai Pharmaceutical Co., Ltd.
For more information, please contact:
Specialty Solutions SBU
Functional Additives Division
Asahi Kasei Corp.
About Business Wire
Subscribe to releases from Business Wire
Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.
Latest releases from Business Wire
Orange Polska Leverages ADTRAN’s Fiber Extension Solutions to Extend FTTH Services30.9.2020 11:00:00 CEST | Press release
https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fportal.adtran.com%2Fweb%2Fpage%2Fportal%2FAdtran%2Fwp_home&esheet=52297558&newsitemid=20200930005145&lan=en-US&anchor=ADTRAN%26%23174%3B%2C+Inc.&index=1&md5=a2f44128c043e79907dc3239808d7aba ADTRAN®, Inc., (NASDAQ:ADTN), the leading provider of next-generation open networking and subscriber experience solutions, today announced its deployment plans with Orange Polska. Orange, Poland’s leading operator with 28% market share and over 13.7 million active customers, is rapidly rolling out its Fiber-to-the-Home (FTTH) service and has selected https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fwww.adtran.com%2Findex.php%2Fbroadband-access%2Fg-fast&esheet=52297558&newsitemid=20200930005145&lan=en-US&anchor=ADTRAN%26%238217%3Bs+2nd+Generation+Gfast+fiber+extension+solutions&index=3&md5=52a7e862db7c4f566a3e3be6b8e5e7a6 ADTRAN’s 2nd Generation Gfast fiber extension solutions to further accelerate its delivery of high
New Denodo Platform 8.0 Accelerates Hybrid/Multicloud Integration, Automates Data Management with AI/ML, and Boosts Performance30.9.2020 08:00:00 CEST | Press release
Denodo, the leader in data virtualization, today announced that its new Denodo Platform version 8.0 accelerates hybrid/multicloud integration, automates data management with artificial intelligence (AI)/machine learning (ML), and boosts performance with smart query acceleration. By further augmenting the Denodo Platform’s already advanced data integration, management, and delivery capabilities with intelligent recommendations, hyper performance, and PaaS support, Denodo Platform 8.0 advances data virtualization into a logical data fabric. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20200929005427/en/ “Data fabric is a hot, emerging market that delivers a unified, intelligent, and integrated end-to-end platform to support new and emerging use cases,” wrote Noel Yuhanna, VP and principal analyst at Forrester Research, and author of https://cts.businesswire.com/ct/CT?id=smartlink&url=https%3A%2F%2Fwww.denodo.com%2Fen%2Fforrest
Verimatrix Application Shielding Technology Wins CSI Magazine Award30.9.2020 07:15:00 CEST | Press release
Regulatory News: Verimatrix, (Paris:VMX) (Euronext Paris: VMX), the leader in powering the modern connected world with people-centered security, today announced that ProtectMyApp, an application shielding solution for mobile app developers, was named Best Cybersecurity Service in the 18th Annual CSI Magazine Awards. Winners were announced during a virtual broadcast on September 18. Verimatrix’s application shielding technology is routinely recognized for its ability to streamline the implementation of code protection while still providing the most robust security possible for mobile app developers. “It’s crucial to vigorously secure the actual mobile applications that have become such a vital part of our industry,” said Goran Nastic, editor of CSI Magazine. “Delivering increasingly valuable content, mobile apps and their developers can be armed with latest application shielding technologies that result in self-defending apps. Congratulations to Verimatrix for being named the winner of
Aurora Sustainability: Changing the World With the Network Effect30.9.2020 07:00:00 CEST | Press release
«Be the change you want to see in the world,» is a well-worn cliché. However, most of us feel overwhelmed in the face of the climate and environmental challenges. Instead of giving in, Cape Town-based Danielle Laity and her team decided to do something. They’ve started a new community: Aurora Sustainability. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20200929005910/en/ Danielle Laity's new sustainable network, Aurora Sustainability, started in Cape Town, and has already over 10.000 users. Credit: Miris (Photo: Business Wire) “In Cape Town, we feel the need for a more sustainable and fairer world every day. Food security is an issue, the predominantly fossil fuel based electrical grid is under strain and climate change will only exacerbate these problems” says Danielle Laity. On the Aurora community platform, anyone can log on and take a quick quiz that tells you the size of your carbon footprint. The intention is not to co
CellSafe and Dynasty Castle Investments Limited Signed Distribution Agreement for LAMPlex TM RT-qLAMP COVID-19 Detection Assay30.9.2020 06:44:00 CEST | Press release
CellSafe, a specialist in developing diagnostics located at the Republic of Korea and Dynasty Castle Investments Limited, a Hong Kong based company specializing in the procurement, distribution and delivery of medical supplies, today announced that they have signed an exclusive distribution agreement for Portugal and 6 African countries for the sale and distribution of LAMPlexTM RT-qLAMP COVID-19 Detection Assay, real-time reverse transcription loop-mediated isothermal amplification (LAMP) technology-based kit which can detect the novel corona virus within 25 minutes. DCI has the rights to supply this clinically proven, reliable FAST molecular diagnostic kit in such countries in partnership with its local distributors. As this global pandemic is raging across the world, CellSafe has cooperated with Armed Forces Medical Research Institute, Republic of Korea to develop and launch LAMPlexTM RT-qLAMP COVID-19 Detection Assay. “This unprecedented pandemic is affecting our lives everywhere.
bitFlyer Europe Launches Cross-Border Trading with Japan to Further Consolidate Global Offering30.9.2020 06:00:00 CEST | Press release
Leading cryptocurrency exchange bitFlyer has announced the launch of cross-border trading on its platform. For the first time, users in Europe will be able to access one of the largest bitcoin markets in Japan, while still using a European-regulated platform. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20200929005920/en/ bitFlyer Europe launches cross-border trading with Japan (Graphic: Business Wire) The Japanese bitcoin market is one of the biggest in the world, with approximately 20%1 of the global BTC to FIAT (national currencies) trading volume being traded against the JPY. As Japan’s leading exchange, more than 70%2 of the JPY trading volume passes through the bitFlyer platform. This makes the launch of cross-border trading a natural next step for bitFlyer in consolidating its position as a global player. bitFlyer is now not only the first cryptocurrency exchange that is licensed to operate in Japan, the EU, and the U
In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.Visit our pressroom