Business Wire

Vifor Pharma reports positive outcome of the phase-IIIb DIAMOND trial of Veltassa ®

Share

Regulatory News:

AD HOC ANNOUNCEMENT PURSUANT TO ART. 53 LR

Vifor Pharma today announced positive findings in the completed phase-IIIb DIAMOND trial of Veltassa® in heart failure patients with either manifest hyperkalemia or with a history of hyperkalemia while treated with renin-angiotensin aldosterone system inhibitor (RAASi) therapy. Veltassa® demonstrated a statistically significant difference versus placebo for the primary endpoint to serum potassium levels in a high risk population.

85% of the more than 1,000 patients with either high risk of hyperkalemia or active hyperkalemia were able to be optimized to guideline recommended, life-saving RAASi treatment, including mineralocorticoid receptor antagonists, with Veltassa® during the run-in phase of the study. This shows that the gap between guideline recommendations and real-world practice regarding the use of RAASi can be addressed with Veltassa®. Veltassa® was generally well tolerated and without unexpected safety findings. Vifor Pharma expects the key trial results to be presented at a major cardiology conference in H1 2022.

“We are delighted and very encouraged about the positive read-out from the DIAMOND trial for the heart failure patient community,” said Dr. Klaus Henning Jensen, Chief Medical Officer of Vifor Pharma. “RAASi therapy saves lives and delays disease progression, but unfortunately many patients with heart failure are insufficiently treated due to risk of hyperkalemia. Hyperkalemia is a serious condition associated with life-threatening consequences. These data support an effective management of chronic hyperkalemia in heart failure patients on optimal RAASi therapy with Veltassa®. We look forward to presenting the detailed data to the scientific community in the first half of 2022.”

“This trial makes a significant contribution to the growing body of evidence showing the importance to use Veltassa® to enable RAASi and ensures optimal treatment in a high-risk population”, commented Prof. Javed Butler, Principal Investigator for the DIAMOND study. “The totality of evidence from the trials with patiromer suggests the treatment to control serum potassium and preventing hyperkalemia in heart failure patients aiding longer term optimal medical therapy.”

Vifor Pharma continues to support several data generation programs with the ongoing phase-IV PLATINUM study and the CARE-HK in HF global registry to drive evidence-based care using Veltassa® in chronic kidney disease and heart failure patients.

About the DIAMOND trial
This global, multicenter, double-blind, placebo controlled study was designed to evaluate the potential role of Veltassa® in enabling patients with, or at high risk of, hyperkalemia to remain on RAASi therapy. On recommendation of the independent study Executive Committee and due to COVID-19 impact on recruitment, the primary endpoint has been changed in June 2021 to investigate the role of Veltassa® in controlling serum potassium, preventing hyperkalemia and maintain RAASi use in heart failure patients.

About Vifor Pharma Group
Vifor Pharma Group is a global pharmaceuticals company. It aims to become the global leader in iron deficiency, nephrology and cardio-renal therapies. The company is a partner of choice for pharmaceuticals and innovative patient-focused solutions. Vifor Pharma Group strives to help patients around the world with severe and chronic diseases lead better, healthier lives. The company develops, manufactures and markets pharmaceutical products for precision patient care. Vifor Pharma Group holds a leading position in all its core business activities and consists of the following companies: Vifor Pharma and Vifor Fresenius Medical Care Renal Pharma (a joint company with Fresenius Medical Care). Vifor Pharma Group is headquartered in Switzerland, and listed on the Swiss Stock Exchange (SIX Swiss Exchange, VIFN, ISIN: CH0364749348).
For more information, please visit viforpharma.com.

To view this piece of content from cts.businesswire.com, please give your consent at the top of this page.

Contact information

Contacts and further information:

Media Relations
Nathalie Ponnier
Global Head Corporate Communications
+41 79 957 96 73
media@viforpharma.com

Investor Relations
Laurent de Weck
Investor Relations & Treasury Senior Manager
+41 58 851 66 90
investors@viforpharma.com

About Business Wire

Business Wire
Business Wire



Subscribe to releases from Business Wire

Subscribe to all the latest releases from Business Wire by registering your e-mail address below. You can unsubscribe at any time.

Latest releases from Business Wire

Mohammed bin Rashid honours 10 Winners of 2022 Zayed Sustainability Prize18.1.2022 16:02:00 CET | Press release

His Highness Sheikh Mohammed bin Rashid Al Maktoum, Vice President, Prime Minister and Ruler of Dubai, presented awards to the 10 winners of the 2022 Zayed Sustainability Prize yesterday. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20220118005713/en/ Mohammed bin Rashid honours 10 Winners of 2022 Zayed Sustainability Prize (Photo: AETOSWire) The Prize’s Awards Ceremony coincided with the start of the 2022 Abu Dhabi Sustainability Week (ADSW). The ceremony was also attended by H.H. Sheikh Maktoum bin Mohammed bin Rashid Al Maktoum, Deputy Ruler of Dubai, Deputy Prime Minister and Minister of Finance. His Highness Sheikh Mohammed bin Rashid Al Maktoum congratulated winners across the five categories reaffirming the Prize’s key role in realising the aspirations of participants to achieve sustainable development within their communities. This year, the Zayed Sustainability Prize, along with ADSW, joined forces with Expo 2020 Du

Pricefx Closes 2021 With Best Quarter in Company History18.1.2022 15:30:00 CET | Press release

Pricefx, the global leader in cloud pricing software, today announced it closed the best quarter in company history due to strong customer and partner traction in 2021. With 26 deals closed in Q4 2021 and 34 new enterprise customers added in 2021, the company ended the year with 45% year-over-year annual recurring revenue (ARR) growth. Key new customers include American Tire Distributors, Extreme Networks, KeHe Distributors and Tamko Building Products. Additionally, Pricefx recorded 95% customer retention and closed 23 customer expansion deals. In 2021, Pricefx increased revenue growth with SAP by 140% over 2020. The Advantage Pricefx partner program continued to drive significant return on investment in 2021 with at least one partner engaged on 70% of new customers signed through co-selling, influencing, and/or implementing the Pricefx solution. Several global system integrators, such as the KPMG German member firm, joined Pricefx’s ecosystem broadening the company’s reach and deepeni

Andersen Global Broadens Footprint in Asian Market through Collaboration with Law Firm in Sri Lanka18.1.2022 15:30:00 CET | Press release

Andersen Global continues to expand its platform in the Asian market through a Collaboration Agreement with Varners, one of the largest full-service law firms in Sri Lanka. Led by Managing Partner Mahinda Haradasa, Varners specializes in banking and finance, commercial, intellectual property, litigation, real estate and telecommunications, international trade and dispute resolution. Located in Colombo, the firm operates with eight Partners and more than 50 professionals, serving clients at the local and international level. “Our professionals’ extensive industry knowledge and commitment to stewardship has allowed our firm to continually meet the demands of the ever-evolving legal landscape,” Mahinda said. “Our collaboration with Andersen Global is a milestone for us as we look to increase our global reach and meet our clients’ cross-border needs.” “Varners’ commitment to investing in its people and providing clients with best-in-class solutions resonates with our organization’s values

Weber Inc . Transforms Outdoor Cooking With Innovative 2022 Product Portfolio18.1.2022 15:05:00 CET | Press release

Weber Inc. (NYSE:WEBR), the global leader in outdoor cooking innovation, technology, and products, today unveiled the first three new products in its 2022 grilling portfolio. Designed to fuse the best in smart technology, high-quality materials, performance engineering, and craftsmanship, the 2022 GENESIS Smart Gas Grill, 2022 SMOKEFIRE Wood Fired Pellet Grill, STEALTH Edition, and all-new WEBER CRAFTED Outdoor Kitchen Collection take cooking outdoors to new levels of food discovery and exploration. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20220118005538/en/ Weber Genesis Smart Gas Grill, Model EPX-335. (Photo: Business Wire) “Our product lineup for the upcoming barbecue season pushes the boundaries of the types of cooking that can be done outdoors, including bringing popular methods like flat top cooking and baking right to a WEBER grill,” said Jennifer Bonuso, Senior Vice President and General Manager, Global Product M

Rubicon Opens New Chile Office to Support Increasing Growth Across Latin America18.1.2022 15:00:00 CET | Press release

Rubicon Capital Advisors (“Rubicon”), one of the world’s leading investment banking firms focused on the broader infrastructure, energy and digital sectors, is pleased to announce the opening of a new office in Santiago de Chile. The opening of the Chilean office, which represents Rubicon’s third in the region, supports the firm’s continued global growth and investment in Latin America, which Rubicon considers a key growth market for the firm. Andres Onetto, who recently joined from Scotiabank, will head the firm’s investment banking and principal investment activities in Chile, Argentina, Paraguay and Uruguay in close cooperation with the firms offices in Mexico and Colombia. Felipe Caro will also join the company from Scotiabank as a Senior Analyst. Rubicon intends to make additional hires over the coming months. “I am delighted to join the Rubicon team at this particularly exciting time. The opening of the Chile office will allow clients unparalleled access to the Southern Cone toge

MSCI Announces Strategic Alliance With Menai Financial Group18.1.2022 14:04:00 CET | Press release

MSCI Inc. (NYSE: MSCI), a leading provider of critical decision support tools and services for the global investment community, announced today its collaboration with Menai Financial Group (“Menai”), a leading provider of institutional-grade digital asset investment products and trading services. This strategic alliance marks one of MSCI’s first collaborations in the digital asset space. MSCI will aim to develop innovative tools for institutional investors seeking to capitalize on the growth of blockchain technology and digital assets. The collaboration between MSCI and Menai comes at a time when institutional investors are increasingly considering opportunities within the digital asset class. As investor interest grows, MSCI has recognized the demand for robust frameworks and analytical tools to help provide insights into performance, risk and classification within this emerging asset class. Menai’s expertise in digital assets will support MSCI’s development of the solutions instituti

GreatStar Tools USA Promotes Roberto Izaguirre to Chief Operating Officer18.1.2022 14:00:00 CET | Press release

GreatStar Tools USA, a leading manufacturer of hand tools serving DIY, professional and industrial markets worldwide,announced today it has promoted Roberto Izaguirre to chief operating officer of Arrow Fastener Company, LLC. Previously serving as vice president of global sales for Arrow Fastener, Izaguirre brings 10 years of company leadership experience to the COO position, having collaborated with fellow executive team members to drive Arrow’s revenue growth, market share, and corporate mission. This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20220118005349/en/ Roberto Izaguirre, chief operating officer of Arrow Fastener Company, LLC. (Photo: Business Wire) In his new role, Izaguirre will be responsible for the sales, operations, personnel, facilities, and administration for GreatStar’s Arrow Fastener, Pony Jorgensen, and Goldblatt brands, in addition to leading the strategic, long-term vision for the business. He will also

In our pressroom you can read all our latest releases, find our press contacts, images, documents and other relevant information about us.

Visit our pressroom