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Press OfficeKarolinska Institutet

Tel:+46 (0)8 524 860 77pressinfo@ki.seki.se/pressroom

Karolinska Institutet is one of the world’s leading medical universities. Our vision is to advance knowledge about life and strive towards better health for all. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.

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Very early medication abortion is effective and safe6.11.2024 23:00:00 CET | Pressmeddelande

Clinics and hospitals currently defer medication abortion until ultrasound confirms a pregnancy inside the uterus. However, a large international study led by researchers from Karolinska Institutet now indicates that treatment can be equally effective and safe even before the sixth week of pregnancy. The study is published in The New England Journal of Medicine.

The 2024 Nobel Prize in Physiology or Medicine jointly to Victor Ambros and Gary Ruvkun7.10.2024 12:15:58 CEST | Press Release

The Nobel Assembly at Karolinska Institutet has today decided to award the 2024 Nobel Prize in Physiology or Medicine jointly to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

In a recent study published in Nature, Swedish researchers demonstrate the role of sex hormones in regulating the immune system. This newfound knowledge explains differences between men and women and can be used to develop new immunological medications according to researchers.

Rising temperatures in Africa may increase perinatal deaths3.9.2024 11:00:00 CEST | Pressmeddelande

Heatwaves in sub-Saharan Africa are predicted to become more common due to climate change. A new study by researchers at Karolinska Institutet and others, published in Nature Medicine, reveals a worrying correlation between high temperatures in the final week of pregnancy and an increased risk of stillbirth and early neonatal mortality.

Perineal cut reduces the risk of serious birth injury18.6.2024 13:00:00 CEST | Press Release

In first-time mothers requiring vacuum-assisted delivery, a lateral episiotomy (angled cut) in the tissue between the vaginal and anal opening more than halves the risk of obstetric anal sphincter injury, a severe form of perineal trauma between the vulva and anus. This according to a randomised clinical study led by researchers at Karolinska Institutet and Stockholm’s Danderyd Hospital, the results of which are published in The BMJ.

New doping test can reveal more cheating female athletes11.6.2024 13:00:00 CEST | Press Release

Roughly three times as many male athletes are banned for doping as female. A new doctoral thesis from Karolinska Institutet shows that one possible reason for this is that the doping tests in use fail to take account of women’s varying hormone profile. Instead, an alternative is proposed that includes a blood test and a limit value that allows doping tests for both elite athletes and casual sportspersons.

New test detects more cases of cervical cancer4.6.2024 09:00:00 CEST | Press Release

Researchers at Karolinska Institutet in Sweden and the University of Innsbruck in Austria have developed a simpler and more effective screening method for cervical cancer than the method used today. A comprehensive study published in Nature Medicine shows that the test detects significantly more cancers and precancerous stages.

New drug candidate reverses obesity in mice30.4.2024 09:00:00 CEST | Press Release

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells’ powerhouses, the mitochondria. A study published in Nature Metabolism shows that a specific class of drugs that block mitochondrial function can reverse diet-induced obesity, fatty liver and diabetes in mice.

Unnecessary use of beta-blockers after a heart attack7.4.2024 13:45:00 CEST | Press Release

Half of all patients discharged from hospital after a heart attack are treated with beta-blockers unnecessarily. This is according to a new study published in the New England Journal of Medicine. "I am convinced that this will influence future practice", says Tomas Jernberg, Professor at Karolinska Institutet and lead researcher of the study.

Women with obesity do not need to gain weight during pregnancy, new study suggests28.3.2024 23:30:00 CET | Press Release

The guidelines for weight gain during pregnancy in obese women have long been questioned. New research from Karolinska Institutet supports the idea of lowering or removing the current recommendation of a weight gain of at least 5 kg. The results are published in The Lancet.

New discovery reveals how the egg controls sperm entry14.3.2024 15:00:00 CET | Press Release

After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo. This is according to a new study led by researchers at Karolinska Institutet and published in the journal Cell. The work also explains how mutations in egg coat proteins can cause female infertility and may eventually lead to new contraceptive methods.

ADHD medication linked to reduced mortality12.3.2024 16:00:00 CET | Press Release

Researchers from Karolinska Institutet have shown a link between use of medication for ADHD and a reduced risk of premature death. The risk of death due to unnatural causes, such as accidents and overdoses, can be reduced by a quarter, according to the new study published in JAMA.

Ashley Moffett and Peter Thelin made honorary doctors at Karolinska Institutet1.3.2024 13:38:15 CET | Press Release

Karolinska Institutet has decided to award honorary doctorates to Ashley Moffett, professor emerita at the University of Cambridge, UK, and Peter Thelin, chair of the Swedish Brain Fund, for their important contributions to science and KI, respectively. The formal ceremony will take place at the conferment ceremony in Stockholm City Hall on 26 April.

Fibroblasts in the penis are more important for erectile function than previously thought8.2.2024 19:00:00 CET | Press Release

Regular erections could be important for maintaining erectile function, according to a new study on mice published in Science by researchers at Karolinska Institutet. “We discovered that an increased frequency of erections leads to more fibroblasts that enable erection and vice versa, that a decreased frequency results in fewer of these cells,” says principal investigator Christian Göritz.

Covid vaccine for pregnant women safe for newborn infants6.2.2024 16:00:00 CET | Press Release

No increased risks for babies, and for some serious neonatal complications lower risks. This is the result of the largest study to date on the safety of newborn babies whose mothers were vaccinated against COVID-19 during pregnancy. The study is a collaboration between Swedish and Norwegian researchers and is published in the journal JAMA.

Perinatal depression linked to increased risk of death10.1.2024 23:30:00 CET | Press Release

Women who suffer depression during or after pregnancy have a higher risk of death by both natural and unnatural causes, a new study of childbirth in Sweden published in The BMJ reports. The increased risk peaks in the month after diagnosis but remains elevated for as long as 18 years afterwards.

New COVID vaccine induces good antibody response to mutated viral variants5.1.2024 23:30:00 CET | Press Release

Researchers at Karolinska Institutet and Danderyd Hospital in Sweden have followed recipients of the new updated COVID-19 vaccine and analysed the antibody response to different SARS-CoV-2 variants. The results published in The Lancet Infectious Diseases show a surprisingly strong response to the now dominant and highly mutated Omicron variants.

New method is better able to map immune response and paves way for new treatments7.12.2023 19:00:00 CET | Press Release

A new method, developed at Karolinska Institutet, KTH Royal Institute of Technology and SciLifeLab in Sweden, can identify unique immune cell receptors and their location in tissue, a study published in the journal Science reports. The researchers predict that the method will improve the ability to identify which immune cells contribute to disease processes and open up opportunities to develop novel therapies for numerous diseases.

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